Results 211 to 220 of about 8,718,410 (331)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Cisplatin-mediated activation of NF-κB promotes lung cancer stem cell formation via DNA repair pathways. [PDF]

J Transl Med
Zhang L, Li Q, Liu C, Wu S, Weng G, Wang L, Chen M, Lin W.   +7 more
europepmc   +1 more source

5-Azacytidine Enhances the Radiosensitivity of CNE2 and SUNE1 Cells In Vitro and In Vivo Possibly by Altering DNA Methylation

, 2014
Wei Jiang, Ying-Qin Li, Na Liu, Ying Sun, Qing-Mei He, Ning Jiang, Ya-Fei Xu, Lei Chen, Jun Ma   +8 more
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Nanogold-Lateral Flow Assay for Ginseng DNA Differentiation. [PDF]

Biosensors (Basel)
Tiffere AH, Sojoudi P, Oberc C, Li PCH.
europepmc   +1 more source

Detection of circulating tumor DNA by tumor-informed whole-genome sequencing enables prediction of recurrence in stage III colorectal cancer patients

Amanda Frydendahl, Jesper Nors, Mads H. Rasmussen, Tenna Vesterman Henriksen, Marijana Nesic, Thomas Reinert, Danielle Afterman, Tomer Lauterman, Maja Kuzman, Santiago González, Dunja Glavaš, James Smadback, Dillon Maloney, Jurica Levativ, Michael Yahalom, Ryan Ptashkin, Iman Tavassoly, Zohar Donenhirsh, Eric J. White, Kandasamy Ravi, Ury Alon, Iver Nordentoft, Sia V. Lindskrog, Lars Dyrskjøt, Claudia Jaensch, Uffe S. Løve, Per Vadgaard Andersen, Ole Thorlacius‐Ussing, Lene H. Iversen, Kåre Andersson Gotschalck, Asaf Zviran, Boris Oklander, Claus L. Andersen   +32 more
openalex   +1 more source

DNA and All That [PDF]

, 1972
Benjamin Lewin
openalex   +1 more source

Loop-mediated isothermal amplification of DNA.

Nucleic Acids Research, 2000
T. Notomi, H. Okayama, Harumi Otawara-shi Masubuchi, Toshihiro Yonekawa, Keiko Watanabe, N. Amino, T. Hase   +6 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The Latest Practices in Culture-Free Detection of Bacteria in Water, From Sampling to Membrane Filtration and DNA Extraction: A Systematic Review. [PDF]

Microbiologyopen
Togănel RO, Ciurea CN, Cighir A, Mare AD, Coșeriu RL, Vintilă C, Cucoranu DC, Man A.   +7 more
europepmc   +1 more source