Results 241 to 250 of about 7,795,985 (403)

Comparative performance evaluation of bisulfite- and enzyme-based DNA conversion methods. [PDF]

Clin Epigenetics
Simons RB, Karkala F, Kukk MM, Adams HHH, Kayser M, Vidaki A.   +5 more
europepmc   +1 more source

TWO SEQUENTIAL REPRESSIONS OF DNA SYNTHESIS IN THE ESTABLISHMENT OF LYSOGENY BY PHAGE P22 AND ITS MUTANTS

, 1964
Hamilton O. Smith, Myron Levine
openalex   +1 more source

Inhibition of DNA synthesis in Ehrlich ascites cells by actinomycin D. II. The presynthetic block in the cell cycle. [PDF]

, 1965
Renato Baserga, Richard D. Estensen, Robert O. Petersen   +2 more
openalex   +1 more source

DNA targeting specificity of RNA-guided Cas9 nucleases

Nature Biotechnology, 2013
P. Hsu, David A. Scott, Joshua A Weinstein, F. Ran, S. Konermann, Vineeta Agarwala, Yinqing Li, Eli J. Fine, Xuebing Wu, Ophir Shalem, T. Cradick, L. Marraffini, Gang Bao, Feng Zhang   +13 more
semanticscholar   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Understanding DNA-encoded carbon nanotube sorting and sensing via sub-nm-resolution structural determination. [PDF]

Sci Adv
Li Y, Wen Y, Beltrán LC, Zhu L, Tian S, Liu J, Zhou X, Chen P, Egelman EH, Zheng M, Lin Z.   +10 more
europepmc   +1 more source

D-MANNOSE AS A CONSTITUENT OF THE DNA OF A MUTANT STRAIN OF BACTERIOPHAGE SP8 [PDF]

, 1965
Eugene Rosenberg
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Prognostic value of circulating HPV cell-free DNA in cervical cancer using liquid biopsy. [PDF]

Sci Rep
Gupta A, Dagar G, Das SK, Chauhan R, Shankar A, Sharma DN, Suri V, Khan MA, Macha MA, Ahmed I, Akil ASA, Bhat AA, Singh M.   +12 more
europepmc   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source