Results 271 to 280 of about 8,837,195 (335)

Amphiphilic Cu(II) Oxacyclen Complexes: From Oxidative Cleavage to Condensation of DNA. [PDF]

Chembiochem
Verbitsky O, Hinojosa S, Mostafa A, Ojha D, Bald I, Kulak N.   +5 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV. [PDF]

Elife
Fombellida-Lopez C, Valaitienė A, Winchester L, Maes N, Dellot P, Vanwinge C, Ladang A, Cavalier E, Susin F, Vaira D, Hayette MP, Reenaers C, Moutschen M, Fletcher CV, Pasternak AO, Darcis G.   +15 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Impact of exercise-induced DNA damage repair on age-related muscle weakness and sarcopenia. [PDF]

Front Genet
Zhu L, Su Y, Su Z.
europepmc   +1 more source

Recombination associated with replication of malarial mitochondrial DNA.

, 1996
Peter R. Preiser, Robert Wilson, P. W. Moore, Shirley McCready, M. A. HAJIBAGHERI, K J Blight, Malcolm Strath, Donald H. Williamson   +7 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A framework for optimising arthropod DNA quality and quantity for modern sequencing tools using hard ticks (Ixodidae). [PDF]

Parasitol Res
Barton XW, S Tobe S, Fontaine JB, Oskam CL.   +3 more
europepmc   +1 more source

Assessment of Genetic Diversity in Alfalfa Using DNA Polymorphism Analysis and Statistical Tools [PDF]

C. Petolescu, Ioan Sărac, S. Popescu, Alina-Maria Țenche-Constantinescu, I. Petrescu, D. Camen, A. Turc, G. Fora, Violeta Turcuș, Nicolae Marinel HORABLAGA, Gabriela Gorinoiu, Mariana Ganea, Emilian Onișan   +12 more
openalex   +1 more source