Results 61 to 70 of about 6,270,915 (209)
Method for systematic targeted isolation of homologous cDNA fragments in a multiplex format
BioTechniques, 2004 In this study, a two-step method for systematic multiplex cloning of homologous cDNAs from related species was developed. The first step, called MUCH (multiplex cloning of homologous genes), is cloning of partial but authentic cDNA fragments of ...
Reiko Ohara +3 more
doaj +1 more source
Cell transformation in tumor-development: a result of accumulation of Misrepairs of DNA through many generations of cells [PDF]
arXiv, 2015 Development of a tumor is known to be a result of accumulation of DNA changes in somatic cells. However, the processes of how DNA changes are produced and how they accumulate in somatic cells are not clear. DNA changes include two types: point DNA mutations and chromosome changes.
arxiv
DNA-Correcting Codes in DNA Storage Systems [PDF]
arXiv, 2023 In [1], the authors proposed a new model of DNA storage system that integrates all three steps of retrieval and introduced the concept of DNA-correcting codes, which guarantees that the output of the storage system can be decoded to the original data. They also gave necessary and sufficient conditions for DNA-correcting codes when the data part is free
arxiv
The C Terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit [PDF]
, 1999 Ku is a heterodimeric protein with double-stranded DNA end-binding activity that operates in the process of nonhomologous end joining. Ku is thought to target the DNA-dependent protein kinase (DNA-PK) complex to the DNA and, when DNA bound, can interact ...
Jeggo, P A +4 more
core +2 more sources
Biotechnology for Biofuels, 2019 Background Bio-based production of organic acids promises to be an attractive alternative for the chemicals industry to substitute petrochemicals as building-block chemicals.
Abeer H. Hossain +6 more
doaj +1 more source
SET1/MLL family of proteins: functions beyond histone methylation
Epigenetics, 2021 The SET1 family of enzymes are well known for their involvement in the histone 3 lysine 4 (H3K4) methylation, a conserved trait of euchromatin associated with transcriptional activation.
Jeyapal Sugeedha +2 more
doaj +1 more source
Applications and Challenges of Real-time Mobile DNA Analysis
, 2017 The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA sequencing outside of ...
Ko, Steven Y. +2 more
core +1 more source
Sources of DNA contamination and decontamination procedures in the forensic laboratory [PDF]
, 2011 The sensitivity of forensic DNA typing techniques can cause problems when evidence samples are inadvertently contaminated with DNA from another source. Therefore, precautions need to be taken to minimize the risk of contamination.
De Groote, Sabine +6 more
core +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 CRISPR systems enable targeted genome editing in a wide variety of organisms by introducing single- or double-strand DNA breaks, which are repaired using endogenous molecular pathways.
Gavin Kurgan +13 more
doaj
High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer [PDF]
, 2019 DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC).
Dasgupta, Subhamoy +6 more
core +2 more sources