Results 241 to 250 of about 90,456 (335)

MARCO+ Tumor‐Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma

Advanced Science, EarlyView.
MARCO+ TAMs dominate restrained cytotoxicity of CD8+ CTLs and ICB resistance in RCC. Mechanically, MARCO impairs MHC‐I‐mediated neoantigen cross‐presentation via the SOCS1‐JAK1‐STAT1‐NLRC5 signaling cascade in TAMs. Targeted MARCO treatment boosts macrophage antigen cross‐presentation and empowers CD8+ T cells, thereby potentiating ICB efficacy ...
Jiayuan Chen, Jiazhi Mo, Jinchang Wei, Mengnan Qu, Jie Dai, Yan Kong, Huayan Xu, Juan Li, Xieqiao Yan, Chuanliang Cui, Lu Si, Zhihong Chi, Jun Guo, Xiaowen Wu, Xinan Sheng   +14 more
wiley   +1 more source

DNA Barcoding-Enabled Tracking of Lipid Nanoparticles: Drug-Loading-Dependent Biodistribution and Tumor Microenvironment Targeting. [PDF]

Adv Healthc Mater
Xu L, Chen R, Wang X, Liu D, Liu Y, Zhao CX.   +5 more
europepmc   +1 more source

Countering criticisms of single mitochondrial DNA gene barcoding in birds [PDF]

, 2009
Allan J. Baker, Erika Tavares, Rebecca Elbourne   +2 more
openalex   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

The front‐end logistics of DNA barcoding: challenges and prospects [PDF]

, 2009
Alex Borisenko, Jayme E Sones, Paul D. N. Hebert   +2 more
openalex   +1 more source

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

Advanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang, Minghao Zhang, Qingbo Zheng, Qinran Yu, Guowu Yang, Wenwen Ren, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan   +12 more
wiley   +1 more source

Global consumption of threatened freshwater eels revealed by integrating DNA barcoding, production data, and trade statistics. [PDF]

Sci Rep
Kaifu K, Han YS, Shiraishi H.
europepmc   +1 more source

Identification of ‘extinct’ freshwater mussel species using DNA barcoding

, 2008
David C. Campbell, Paul D. Johnson, James D. Williams, Andrew K. Rindsberg, Jeanne M. Serb, KORY K. SMALL, Charles Lydeard   +6 more
openalex   +2 more sources

A comparative analysis of DNA barcode microarray feature size [PDF]

, 2009
Ron Ammar, Andrew Smith, Lawrence E. Heisler, Guri Giaever, Corey Nislow   +4 more
openalex   +1 more source

Osmotically Tunable Microdroplets Enable Amplification‐Free CRISPR Detection of Gene Doping

Advanced Science, EarlyView.
A novel amplification‐free clustered regularly interspaced short palindromic repeats/CRISPR‐associated protein (CRISPR/Cas) 12a assay is integrated with osmotically shrinkable double emulsion droplets for the rapid and ultrasensitive detection of gene doping.
Jihun Han, Reya Ganguly, Joon‐Yeop Yi, Hyewon Yun, So‐Yeon Jung, Changmin Sung, Chang‐Soo Lee   +6 more
wiley   +1 more source