Results 171 to 180 of about 113,396 (329)

Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp. [PDF]

open access: yesJ Biol Chem, 2020
Hara K   +7 more
europepmc   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

open access: yesExploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen   +8 more
wiley   +1 more source

Hesperetin Mitigate Idiopathic Pulmonary Fibrosis by Regulating Gut Microbiota and Acetate and Butyrate Levels via the Gut‐Lung Axis

open access: yesFood Frontiers, EarlyView.
Hesperetin inhibits bleomycin‐induced idiopathic pulmonary fibrosis by regulating gut microbiota and acetate and butyrate levels via the gut‐lung axis. ABSTRACT In the post‐epidemic and aging era, idiopathic pulmonary fibrosis (IPF) has become one of the major diseases endangering human health.
Xia Meng   +9 more
wiley   +1 more source

Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays

open access: gold, 2020
Winnie Tan   +8 more
openalex   +1 more source

Freeze‐resistant, conductive semi‐interpenetrating network hydrogels enable oxidative stress regulation and enhanced wound healing

open access: yesInterdisciplinary Medicine, EarlyView.
A multifunctional SFMA9/PF1 semi‐interpenetrating hydrogel with excellent conductivity, antioxidant activity, and freeze resistance effectively regulates the wound microenvironment, reduces oxidative stress and inflammation, promotes angiogenesis, and accelerates full‐thickness skin regeneration.
Xiaomin Sun   +7 more
wiley   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

3D Polymeric Nanonetworks: From Self‐Assembly to Advanced Fabrication

open access: yesMacromolecular Materials and Engineering, EarlyView.
This review provides the first systematic cross‐method comparison of fabrication techniques for 3D polymeric nanonetworks. It evaluates five key strategies—block copolymer self‐assembly, hyper‐crosslinking, template‐assisted methods, 3D printing, and nanolithography—across critical metrics including resolution, throughput, scalability, and material ...
Carlos G. Cobos   +2 more
wiley   +1 more source

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