Results 181 to 190 of about 113,396 (329)

Molecular phylogenetic and morphological analyses revealed a new species, Leucocoprinus roseus (Agaricaceae, Basidiomycota), from Punjab, Pakistan

open access: yesNordic Journal of Botany, EarlyView.
In this article, we describe a new fungal species, Leucocoprinus roseus, collected in Canal View Park, District Mandi Bahauddin, Punjab, Pakistan. The species is proposed as new based on detailed morphological observations and molecular phylogenetic analysis using nuclear ribosomal DNA internal transcribed spacer (nrITS) sequences.
Wajahat Akram   +7 more
wiley   +1 more source

Uncovering a new species of Hemileccinum (Boletaceae, Basidiomycota) from India with morphological characteristics and multi‐gene molecular phylogeny

open access: yesNordic Journal of Botany, EarlyView.
While undertaking macrofungal forays to several forested areas of Uttarakhand (India), a noteworthy and previously unknown species of Hemileccinum was unveiled. This species is proposed here as Hemileccinum indicum sp. nov. It is presented with both morphological characteristics and multigene molecular phylogenetic analysis.
Kanad Das   +3 more
wiley   +1 more source

Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation

open access: yesNature Communications
DNA segregation by bacterial ParABS systems is mediated by transient tethering interactions between nucleoid-bound dimers of the ATPase ParA and centromere (parS)-associated complexes of the clamp-forming CTPase ParB.
Lucas Schnabel   +10 more
doaj   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. [PDF]

open access: yesNucleic Acids Res, 2016
Altieri AS   +6 more
europepmc   +2 more sources

Arbuscular mycorrhiza in the urban jungle: Glomeromycotina communities of the dominant city tree across Amsterdam

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Trees in cities provide a great number of benefits to people and nature, but they are challenged by harsh conditions. Trees rely on helpful fungi in their roots to get essential nutrients from the soil, but we do not know which of these fungi are resistant to city landscapes.
Casper T. Verbeek   +2 more
wiley   +1 more source

Human Citrate Synthase Post‐Translational Modification Mimics and Molecular Dynamic Simulations Demonstrate Attenuation of Acetyl‐CoA/CoA Binding

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human citrate synthase (hCS) is a mitochondrial enzyme that catalyzes the aldol condensation of acetyl coenzyme A (AcCoA) to oxaloacetate to form citrate in the TCA cycle. CS activity is important for aerobic exercise performance and basic metabolic function as a housekeeping enzyme.
Noah Shackelford   +3 more
wiley   +1 more source

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy