Results 191 to 200 of about 113,396 (329)

Physical and functional interplay between PCNA DNA clamp and Mre11-Rad50 complex from the archaeon Pyrococcus furiosus. [PDF]

Nucleic Acids Res, 2018
Hogrel G, Lu Y, Laurent S, Henry E, Etienne C, Phung DK, Dulermo R, Bossé A, Pluchon PF, Clouet-d'Orval B, Flament D.   +10 more
europepmc   +1 more source

Faculty Opinions recommendation of Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.

, 2020
Antony M. Carr
openalex   +2 more sources

Dynamics of Loading the β Sliding Clamp of DNA Polymerase III onto DNA [PDF]

, 1996
Linda B. Bloom, Jennifer Turner, Zvi Kelman, Joseph Beechem, Mike O’Donnell, Myron F. Goodman   +5 more
openalex   +1 more source

Substrate‐Tight Graphene Transmembrane‐nanofluidic Devices

Small, EarlyView.
This study demonstrates that the covalent coupling of a pyrene layer to a silicon nitride substrate using silane and peptide chemistry increases the adhesion of graphene to the substrate and prevents the delamination of graphene. 76.2% of the devices with free‐standing graphene are successful devices for ion transport measurement in 0.1 M HCl ...
Xiaofang Kang, Buhang Chen, Erik P. van Geest, Wangyang Fu, Jianwei Gao, Luzhao Sun, Zhongfan Liu, Grégory F. Schneider   +7 more
wiley   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling. [PDF]

Nucleic Acids Res, 2018
Gadkari VV, Harvey SR, Raper AT, Chu WT, Wang J, Wysocki VH, Suo Z.   +6 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

DNA recognition and induced genome modification by a hydroxymethyl-γ tail-clamp peptide nucleic acid

, 2023
Stanley N. Oyaghire, Elias Quijano, Julián Perera, Hanna K. Mandl, W. Mark Saltzman, Raman Bahal, Peter M. Glazer   +6 more
openalex   +1 more source

The sliding clamp of DNA polymerase III holoenzyme encircles DNA. [PDF]

Molecular Biology of the Cell, 1992
M, O'Donnell, J, Kuriyan, X P, Kong, P T, Stukenberg, R, Onrust   +4 more
openaire   +2 more sources

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source