Results 211 to 220 of about 113,396 (329)

Interferon Regulatory Factor 2 (IRF2) Suppression Enhances Murine Cardiac Allograft Survival Through Immune Evasion

Immunology, EarlyView.
Our data show that suppressing IRF2, genetically or by siRNA, modulates PD‐L1 and MHC‐I levels. This induced immune‐evasive state critically underlies the significantly prolonged survival of cardiac allografts, revealing a novel therapeutic avenue.
Li Tian, Man Zhang, Yuliang Guo, Sheng Chang, Zhonghua Klaus Chen, Hongmin Zhou   +5 more
wiley   +1 more source

Author response: MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA

, 2015
F.S. Groothuizen, I. Winkler, Michele Cristóvão, Alexander Fish, H.H.K. Winterwerp, Annet Reumer, Andreas D. Marx, Nicolaas Hermans, Robert A. Nicholls, Garib N. Murshudov, Joyce H.G. Lebbink, Peter Friedhoff, Titia K. Sixma   +12 more
openalex   +1 more source

Structural insight into β-Clamp and its interaction with DNA Ligase in Helicobacter pylori [PDF]

, 2016
Preeti Pandey, K.F. Tarique, Mohit Mazumder, S.A. Abdul Rehman, Nilima Kumari, Samudrala Gourinath   +5 more
openalex   +1 more source

Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby [PDF]

, 2020
Pengyu Hao, Sharonda LeBlanc, Brandon C. Case, Timothy C. Elston, Manju Hingorani, Dorothy A. Erie, Keith Weninger   +6 more
openalex   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

Journal of Fish Biology, EarlyView.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne, Stanislas Pilet, Sean Heighton, Benoît Bernay, Pascal Sourdaine   +4 more
wiley   +1 more source

The ATPase Reaction of S. cerevisiae RFC Reveals a Finely Choreographed Mechanism for Loading PCNA Clamps on DNA [PDF]

, 2009
Yayan Zhou
openalex   +1 more source

Bacillus subtilis RNase HII Is Inefficient at Processing Guanosine Monophosphate and Damaged Ribonucleotides

Molecular Microbiology, EarlyView.
Bacillus subtilis RNase HII corrects ribonucleotide errors and mismatched ribonucleotides, but not damaged ribonucleotides. Mismatched ribonucleotides would also serve as substrates for mismatch repair while damaged ribonucleotides would be addressed through base excision repair.
Julianna R. Cresti, Lyle A. Simmons
wiley   +1 more source

Molecular force spectroscopy with a DNA origami–based nanoscopic force clamp

, 2016
Philipp C. Nickels, B. Wünsch, Phil Holzmeister, Wooli Bae, Luisa Kneer, Dina Grohmann, Philip Tinnefeld, Tim Liedl   +7 more
openalex   +2 more sources

Increased dNTP Binding Affinity Reveals a Nonprocessive Role for Escherichia coli β Clamp with DNA Polymerase IV [PDF]

, 2004
Jeffrey G. Bertram, Linda B. Bloom, Mike O’Donnell, Myron F. Goodman   +3 more
openalex   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Obesity Reviews, EarlyView.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source