Results 231 to 240 of about 113,396 (329)

Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism

open access: green, 2021
Benedikt Bauer   +8 more
openalex   +2 more sources

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

open access: yesVeterinary Dermatology, EarlyView.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann   +2 more
wiley   +1 more source

Simulative and Experimental Characterization of a pH-Dependent Clamp-like DNA Triple-Helix Nanoswitch

open access: green, 2017
Federico Iacovelli   +7 more
openalex   +2 more sources

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

open access: yesExperimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu   +8 more
wiley   +1 more source

A non-catalytic role for RFC in PCNA-mediated processive DNA synthesis. [PDF]

open access: yesCell
Chua GNL   +12 more
europepmc   +1 more source

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

open access: yesExperimental Physiology, EarlyView.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová   +10 more
wiley   +1 more source

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