Results 241 to 250 of about 113,396 (329)

Structural Analyses of gp45 Sliding Clamp Interactions during Assembly of the Bacteriophage T4 DNA Polymerase Holoenzyme

, 1997
Gary J. Latham, Daniel J. Bacheller, Paola Pietroni, Peter H. von Hippel   +3 more
openalex   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

Experimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson, Man Si, Krystle Trosclair, Ellen Aughenbaugh, Maxine Parkinson, Nicole M. Gautier‐Hall, Megan Watts, Frederica Kizek, Md. Shenuarin Bhuiyan, Paari Dominic, Kathryn A. Hamilton, Edward Glasscock   +11 more
wiley   +1 more source

Structural insights into the exchange mechanism of a replicative DNA polymerase. [PDF]

Nucleic Acids Res
Feng X, Spiering MM, Ruda de Luna Santos A, Benkovic SJ, Li H.   +4 more
europepmc   +1 more source

Genetic Interactions between the Escherichia coli umuDC Gene Products and the β Processivity Clamp of the Replicative DNA Polymerase

, 2001
Mark D. Sutton, Mary F. Farrow, Briana M. Burton, Graham C. Walker   +3 more
openalex   +1 more source

Interplay MutS with β Clamp on Mismatched DNA [PDF]

, 2015
Jungsic Oh, Daehyung Kim, Won‐Ki Cho, Jiaquan Liu, Slobodan Jergic, Nicholas E. Dixon, Richard Fishel, Jong‐Bong Lee   +7 more
openalex   +1 more source

The cardiac pacemakers: A paradigm of robustness in evolutionary biology

The Journal of Physiology, EarlyView.
Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

The Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford, Georgia Fakonti, Ziyu Shao, Sharanam Soni, Sophie L. Earle, Muath Bajarwan, Lara C. Morley, Beth Holder, Eleanor M. Scott, Karen Forbes   +9 more
wiley   +1 more source

PCNA is a nucleotide exchange factor for the clamp loader ATPase complex. [PDF]

Proc Natl Acad Sci U S A
Pajak J, Landeck JT, Liu X, Anand K, Litvak S, Kelch BA.   +5 more
europepmc   +1 more source

Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping [PDF]

, 2013
Hye-Ryoun Kim, Sung Yong Lee, Dae-Sung Hyun, Min Ki Lee, Hyun-Kyung Lee, Chang‐Min Choi, Sei-Hoon Yang, Young‐Chul Kim, Yong Chul Lee, Seon Young Kim, Seung Hun Jang, Jae Cheol Lee, Kye Young Lee   +12 more
openalex   +1 more source

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

The Journal of Physiology, EarlyView.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid, Francisco Algaba‐Chueca, Elsa Maymó‐Masip, Mónica Ballesteros, Montse Inglés, Albert Guarque, Nerea Vilanova‐Ricart, Ariadna Prats, Azra Kulovic‐Sissawo, Elisa Weiss, Ursula Hiden, Joan Vendrell, Sonia Fernández‐Veledo, Ana Megía   +13 more
wiley   +1 more source