Results 261 to 270 of about 113,396 (329)

FANCD2-FANCI is a sliding DNA clamp that specifically recognizes ss/ds-DNA junctions [PDF]

Pablo Alcón, Artur Kaczmarczyk, Tamara Sijacki, Lori A. Passmore, David Rueda   +4 more
openalex   +1 more source

Covalent Peptide‐Based N‐Myc/Aurora‐A Inhibitors Bearing Sulfonyl Fluoride Warheads

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
N‐Myc‐derived peptidomimetics bearing aryl sulfonyl fluoride warheads were shown to act as effective N‐Myc/Aurora‐A PPI inhibitors, selectively labelling Aurora‐A in a recognition‐directed manner. ABSTRACT Orthosteric inhibition of the N‐Myc/Aurora‐A protein–protein interaction (PPI) represents a potential mechanism by which degradation of N‐Myc can be
Robert S. Dawber, Diana Gimenez, George W. Preston, Megan H. Wright, Richard Bayliss, Stuart L. Warriner, Andrew J. Wilson   +6 more
wiley   +1 more source

Structural evolution of the selectivity clamp confers ADPR-PP specificity in Namat, a phage nicotinamide ADP-ribose transferase. [PDF]

Nucleic Acids Res
Lan M, Xu L, Han Y, Cui T, Qiao Z, Teng YB, Wang N, Bao H.   +7 more
europepmc   +1 more source

Human Dorsal Root Ganglia Neuronal Cell Line to Study Nociceptive Signaling: A New Pipeline for Pain Therapy

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
The nociceptive properties of differentiated human HD10.6 cells were characterized by multiple approaches (A). Peripheral sensitization was induced within HD10.6 cells in response to an inflammatory cocktail (B), modeling nociceptors in a chronic pain state.
Sara A. Dochnal, Yixing Du, Daniella Bandari, Kaue Franco Malange, Jack Bryant, Julia Borges Paes Lemes, Abby Whitford, Anna R. Cliffe, Prashant Mali, Kim Dore, Yury I. Miller, Tony L. Yaksh   +11 more
wiley   +1 more source

Responses to Ligand Binding in the Bacterial DNA Sliding Clamp "β-Clamp" Manifest in Dynamic Allosteric Effects. [PDF]

Proteins
Simonsen S, Prestel A, Østerlund EC, Otterlei M, Jørgensen TJD, Kragelund BB.   +5 more
europepmc   +1 more source

Harnessing Non‐Covalent Protein–Protein Interaction Domains for Production of Biocatalytic Materials Systems

Advanced Functional Materials, Volume 36, Issue 11, 5 February 2026.
Non‐covalent protein–protein interactions mediated by SH3, PDZ, or GBD domains enable the self‐assembly of stable and biocatalytically active hydrogel materials. These soft materials can be processed into monodisperse foams that, once dried, exhibit enhanced mechanical stability and activity and are easily integrated into microstructured flow ...
Julian S. Hertel, Maria Alessandra Martini, Marius Stoeckle, Annika J. Weber, Kersten S. Rabe, Christof M. Niemeyer   +5 more
wiley   +1 more source

Investigating Polarity Effects in DNA Base Stacking. [PDF]

JACS Au
Abraham Punnoose J, Kam CS, Melfi T, Vangaveti S, Chen AA, Halvorsen K.   +5 more
europepmc   +1 more source

Autonomous Spatiotemporal Regulation of Reversible Hydrogel Actuators by Chemical Reaction Networks

Advanced Materials, Volume 38, Issue 7, 2 February 2026.
Hydrogel actuators with reversible response to thiols are developed using reversible binding of thiols to Michael acceptors. Autonomous spatiotemporal regulation of reversible movement of these hydrogels is achieved using thiol‐based chemical reaction networks containing both positive and negative feedback.
Fan Liao, Ajith George, Xiao‐Meng Sui, Sergey N. Semenov   +3 more
wiley   +1 more source

Orchestrated long-distance gene activation by a ParB-like BisD-CTP DNA clamp in low-frequency transfer competence development inPseudomonas putida

Antar H, Carraro N, Gruber S, van der Meer JR.   +3 more
europepmc   +1 more source

Electroporation of Whole-Mount Postnatal Rodent Retinas for Advanced Functional Assays. [PDF]

Bio Protoc
Huang CT, Chen TJ, Su YL, Tseng CC, Chen PC, Wang CT.   +5 more
europepmc   +1 more source