Results 101 to 110 of about 791,786 (291)

Unlocking the chromatin code by deciphering protein–DNA interactions

Molecular Systems Biology, 2016
Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation.
Dalila Bensaddek, Angus I Lamond
doaj   +1 more source

A Curative DNA Code for Hematopoietic Defects: Novel Cell Therapies for Monogenic Diseases of the Blood and Immune System. [PDF]

Hematol Oncol Clin North Am, 2022
Porteus MH, Pavel-Dinu M, Pai SY.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Food Anti-counterfeiting and Traceability Based on DNA Storage: Technology, Challenges and Prospects [PDF]

Shipin Kexue
Food anti-counterfeiting and traceability are important ways to ensure food safety. In response to the upgrading of counterfeiting means, a variety of identification technologies have been gradually developed, which play a crucial role in the field of ...
SONG Yafeng, XING Ranran, LIANG Xiaoke, GONG Na, ZHEN Zixuan, ZHANG Jiukai, CHEN Ying
doaj   +1 more source

DNA QR Codes

, 2013
Came across this paper recently:Despite QR Codes being uncool, there's something appealing about the idea of compressing a DNA barcode sequence into a small image.
openaire   +1 more source

Properties of Maxentropic DNA Synthesis Codes

Entropy
Low-weight codes have been proposed for efficiently synthesizing deoxyribonucleic acid (DNA) for massive data storage, where a multiple of DNA strands are synthesized in parallel. We report on the redundancy and information rate of maxentropic low-weight codes for asymptotically large codeword length. We compare the performance of low-complexity nibble
Kees Schouhamer Immink, Jos H. Weber, Kui Cai   +2 more
openaire   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Grup Kuosien Sebagai Representasi Dari Kode Genetik Standar Berdasarkan Kimia Nukleotida

Jurnal Matematika Integratif, 2017
ABSTRAK Kode genetik adalah satu set instruksi untuk mentransfer data genetik yang tersimpan dalam bentuk DNA atau RNA menjadi protein. Pada kajian Montano et al [3], kumpulan basa nitrogen dalam rantai RNA dihimpun dan disajikan dalam suatu ...
Isah Aisah, Nurul Ulla
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source