Results 41 to 50 of about 385,672 (266)
Life is a property of matter [PDF]
Agroznanje, 2012 If it is known that the entirety of life on Earth is represented by the certain association of molecules organized in accordance to the code written in another separate association of the molecules named DNA, and knowing that all biological life on Earth
Mićić Nikola
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Genomics dataset of unidentified disclosed isolates
Data in Brief, 2016 Analysis of DNA sequences is necessary for higher hierarchical classification of the organisms. It gives clues about the characteristics of organisms and their taxonomic position. This dataset is chosen to find complexities in the unidentified DNA in the
Bhagwan N. Rekadwad
doaj +1 more source
Malaya Journal of Matematik, 2023 In this paper, by using three different methods, the DNA codes are obtained from some codes over a family of the rings $D_{i}=D_{1}\left[ w_{2},...,w_{i}\right]/\left\langle w_{i}^{2}-w_{i},w_{i}w_{j}-w_{j}w_{i}\right\rangle $, where $% i=2,...,r,j=1,2,...r$ and $D_{1}=F_{2}+uF_{2}+w_{1}(F_{2}+uF_{2}),u^{2}=0,w_{1}^{2}=w_{1},uw_{1}=w_{1}u, F_{2}=\{0,1\}
null Abdullah DERTLI +1 more
openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Informationstheoretisches Modell der Carcinogenese
CHIMIA, 1972 The effects of chemical and physical agents on genetic material have been explained by the interaction of the cell with its immediate environment. Another possibility of cancerogenesis stems from the thermodynamic- and information theory-based premise ...
H. Schaltegger
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
DNA-based watermarks using the DNA-Crypt algorithm
BMC Bioinformatics, 2007 Background The aim of this paper is to demonstrate the application of watermarks based on DNA sequences to identify the unauthorized use of genetically modified organisms (GMOs) protected by patents.
Barnekow Angelika, Heider Dominik
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source