Results 21 to 30 of about 2,751,270 (241)

PhyloCSF: a comparative genomics method to distinguish protein-coding and non-coding regions [PDF]

, 2010
As high-throughput transcriptome sequencing provides evidence for novel transcripts in many species, there is a renewed need for accurate methods to classify small genomic regions as protein-coding or non-coding.
Manolis Kellis, Lin, Michael F., Kellis, Manolis, Irwin Jungreis, Michael F. Lin, Jungreis, Irwin   +5 more
core   +1 more source

At the intersection of non-coding transcription, DNA repair, chromatin structure, and cellular senescence

Frontiers in Genetics, 2013
It is well accepted that non-coding RNAs play a critical role in regulating gene expression. Recent paradigm-setting studies are now revealing that non-coding RNAs, other than microRNAs, also play intriguing roles in the maintenance of chromatin ...
Ryosuke eOhsawa, Ja-Hwan eSeol, Jessica Kate Tyler   +2 more
doaj   +1 more source

Epigenetics: Recent Advances and Its Role in the Treatment of Alzheimer's Disease

Frontiers in Neurology, 2020
Objective: This review summarizes recent findings on the epigenetics of Alzheimer's disease (AD) and provides therapeutic strategies for AD.Methods: We searched the following keywords: “genetics,” “epigenetics,” “Alzheimer's disease,” “DNA methylation,” “
Xuewen Xiao, Xixi Liu, Bin Jiao, Bin Jiao, Bin Jiao   +4 more
doaj   +1 more source

Simple structural differences between coding and noncoding DNA. [PDF]

PLoS ONE, 2011
The study of large-scale genome structure has revealed patterns suggesting the influence of evolutionary constraints on genome evolution. However, the results of these studies can be difficult to interpret due to the conceptual complexity of the analyses.
Kenneth J Locey, Ethan P White
doaj   +1 more source

Dysregulation of Transposon Transcription Profiles in Cancer Cells Resembles That of Embryonic Stem Cells

Current Issues in Molecular Biology
Transposable elements (TEs) comprise a substantial portion of the mammalian genome, with potential implications for both embryonic development and cancer.
Anna I. Solovyeva, Roman V. Afanasev, Marina A. Popova, Natella I. Enukashvily   +3 more
doaj   +1 more source

Analysis of a circular code model [PDF]

, 2001
A circular code has been identified in the protein (coding) genes of both eukaryotes and prokaryotes by using a statistical method called Trinucleotide Frequency method (TF method) [Arquès & Michel, (1996) J.Theor. Biol. 182, 45-58].
Lacan, Jérôme, Michel, Christian
core   +1 more source

Gene expression divergence is coupled to evolution of DNA structure in coding regions. [PDF]

PLoS Computational Biology, 2011
Sequence changes in coding region and regulatory region of the gene itself (cis) determine most of gene expression divergence between closely related species.
Zhiming Dai, Xianhua Dai
doaj   +1 more source

Evolutionary approach to construct robust codes for DNA-based data storage

Frontiers in Genetics, 2023
DNA is a practical storage medium with high density, durability, and capacity to accommodate exponentially growing data volumes. A DNA sequence structure is a biocomputing problem that requires satisfying bioconstraints to design robust sequences ...
Abdur Rasool, Abdur Rasool, Qingshan Jiang, Yang Wang, Xiaoluo Huang, Qiang Qu, Junbiao Dai   +6 more
doaj   +1 more source

Genotyping human ancient mtDNA control and coding region polymorphisms with a multiplexed Single-Base-Extension assay: the singular maternal history of the Tyrolean Iceman [PDF]

, 2009
Background Progress in the field of human ancient DNA studies has been severely restricted due to the myriad sources of potential contamination, and because of the pronounced difficulty in identifying authentic results.
Endicott, Phillip, Cooper, Alan, Pramstaller Peter, Irene Pichler, Pichler Irene, Pichler, I., Brotherton, Paul, Brotherton Paul, Brooks, J., Egarter-Vigl Eduard, Sanchez, J., Pichler, Irene, Egarter-Vigl, E., Sanchez, Juan J, Cooper Alan, Eduard Egarter-Vigl, Brooks Jerome, Pramstaller, Peter, Jerome Brooks, Juan J Sanchez, Alan Cooper, Egarter-Vigl, Eduard, Brotherton, P., Sanchez Juan J, Cooper, A., Brooks, Jerome, Pramstaller, P., Paul Brotherton, Endicott, P., Peter Pramstaller, Endicott Phillip, Phillip Endicott   +31 more
core   +1 more source

Research and developments of distributed video coding [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The recent developed Distributed Video Coding (DVC) is typically suitable for the applications such as wireless/wired video sensor network, mobile camera ...
Xue, Zhuo
core   +7 more sources