Results 41 to 50 of about 1,155,163 (294)
Coding over Sets for DNA Storage
, 2018 In this paper, we study error-correcting codes for the storage of data in synthetic deoxyribonucleic acid (DNA). We investigate a storage model where data is represented by an unordered set of $M$ sequences, each of length $L$.
Lenz, Andreas +3 more
core +1 more source
On the nucleotide distribution in bacterial DNA sequences [PDF]
, 2010 It is probable that the distributional structure of DNA sequences arises from the accumulation of many successive stochastic events such as nucleotide deletions, insertions, substitutions and elongations [1, 2, 3, 4, 5, 6, 7].
Andrew Glenn Hart, Marcelo Sobottka
core +2 more sources
The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster. [PDF]
, 2016 Despite decades of work, our understanding of the distribution of fitness effects of segregating genetic variants in natural populations remains largely incomplete. One form of selection that can maintain genetic variation is spatially varying selection,
Begun, David J +3 more
core +4 more sources
BMC Bioinformatics, 2006 Background Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unraveling the functional significance of non-coding DNA depends on how well we are
Johnson Toby +2 more
doaj +1 more source
Evolutionary approach to construct robust codes for DNA-based data storage
Frontiers in Genetics, 2023 DNA is a practical storage medium with high density, durability, and capacity to accommodate exponentially growing data volumes. A DNA sequence structure is a biocomputing problem that requires satisfying bioconstraints to design robust sequences ...
Abdur Rasool +6 more
doaj +1 more source
EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks [PDF]
, 2019 The exosome is a ribonucleolytic complex that plays important roles in RNA metabolism. Here we show that the exosome is necessary for the repair of DNA double-strand breaks (DSBs) in human cells and that RNA clearance is an essential step in homologous ...
Bonath, Franziska +7 more
core +2 more sources
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
BMC Bioinformatics, 2005 Background Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficult problem.
Bininda-Emonds Olaf RP
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Application of Machine Learning to Environmental DNA Metabarcoding
IEEE Access, 2022 Machine learning is known as an effective technique to classify big data, and coding methods for input into neural networks are critical. In this study, we have applied the machine learning to environmental deoxyribonucleic acid (DNA) metabarcoding.
Mutsumi Kimura +2 more
doaj +1 more source
Characteristic Length Scale of Electric Transport Properties of Genomes
, 2005 A tight-binding model together with a novel statistical method are used to investigate the relation between the sequence-dependent electric transport properties and the sequences of protein-coding regions of complete genomes.
C. T. Shih +3 more
core +1 more source