Results 51 to 60 of about 2,863,112 (293)
For $q$-ary $n$-sequences, we develop the concept of similarity functions that can be used (for $q=4$) to model a thermodynamic similarity on DNA sequences. A similarity function is identified by the length of a longest common subsequence between two $q$-ary $n$-sequences. Codes based on similarity functions are called DNA codes.
openaire +3 more sources
Aligned TLR8 Coding DNA Sequences
The Aligned TLR8 coding DNA sequences, pulled from Ensemble.org for Pig, Choacoan Peccary, Cow, Wild Yak, Chicken and Red Junglefowl. Was aligned through AliView, and used for Blast, imed and DNSsp6 analysis.
Madison Ryan (14782129)
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Aligned TLR7 Coding DNA sequences
The Aligned TLR7 coding DNA sequences, pulled from Ensemble.org for Pig, Choacoan Peccary, Cow, Wild Yak, Chicken and Red Junglefowl. Was aligned through AliView, and used for Blast, imed and DNSsp6 analysis.
Madison Ryan (14782129)
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficult problem.
Bininda-Emonds Olaf RP
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Numerical sequence representation of DNA sequences and methods to distinguish coding and non-coding sequences in a complete genome [PDF]
In this presentation we introduce two methods to distinguish coding and non-coding sequences in a complete genome. A numerical sequence representation of DNA sequences is introduced first.\ud There exists a one-to-one correspondence between a DNA ...
Anh, Vo V. +3 more
core
Genotyping human ancient mtDNA control and coding region polymorphisms with a multiplexed Single-Base-Extension assay: the singular maternal history of the Tyrolean Iceman [PDF]
Background Progress in the field of human ancient DNA studies has been severely restricted due to the myriad sources of potential contamination, and because of the pronounced difficulty in identifying authentic results.
Endicott, Phillip +31 more
core +1 more source

