Results 51 to 60 of about 736,909 (260)

Application of Machine Learning to Environmental DNA Metabarcoding

open access: yesIEEE Access, 2022
Machine learning is known as an effective technique to classify big data, and coding methods for input into neural networks are critical. In this study, we have applied the machine learning to environmental deoxyribonucleic acid (DNA) metabarcoding.
Mutsumi Kimura   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Color Image Encryption Algorithm Based on Chaotic System and Dynamic DNA Coding and Operation [PDF]

open access: yesJisuanji gongcheng, 2018
Aiming at the problem that the chaos based image encryption algorithm combined with DNA coding can be broken caused by incorrect use of DNA coding rules and calculation methods,a new image encryption algorithm combined Intertwining Logistic mapping and ...
YANG Jiyun,WU Hao
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Functions of human non-coding dna sequences [PDF]

open access: yesArchive of Oncology, 2011
The development of string theory has opened a completely new chapter and the way of thinking. A tight connection between DNA, water and strings, as well as their properties, lead to the idea that the soul is the shelter of our thoughts. Only 2% of the
Stupar Milanko   +2 more
doaj   +1 more source

An Adaptive Mapping Method Using Spectral Envelope Approach for DNA Spectral Analysis

open access: yesEntropy, 2022
The digital signal processing approaches were investigated as a preliminary indicator for discriminating between the protein coding and non-coding regions of DNA.
Milena Arruda   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Quantitative sequence and open reading frame analysis based on codon bias [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2006
The frequencies with which the sixty-four codons occur in human coding DNA are known. If we assume that the codons occur randomly, subject only to these probabilities, then it is possible to predict trinucleotide frequencies in each of the five other ...
Susan Rainey, Joe Repka
doaj  

Linear constructions for DNA codes

open access: yesTheoretical Computer Science, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gaborit, Philippe, King, Olivier D.
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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