Results 61 to 70 of about 2,863,112 (293)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Color Image Encryption Algorithm Based on Chaotic System and Dynamic DNA Coding and Operation [PDF]
Aiming at the problem that the chaos based image encryption algorithm combined with DNA coding can be broken caused by incorrect use of DNA coding rules and calculation methods,a new image encryption algorithm combined Intertwining Logistic mapping and ...
YANG Jiyun,WU Hao
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Application of Machine Learning to Environmental DNA Metabarcoding
Machine learning is known as an effective technique to classify big data, and coding methods for input into neural networks are critical. In this study, we have applied the machine learning to environmental deoxyribonucleic acid (DNA) metabarcoding.
Mutsumi Kimura +2 more
doaj +1 more source
Linear constructions for DNA codes
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Gaborit, Philippe, King, Olivier D.
openaire +2 more sources
CpG dinucleotide frequencies in coding DNA sequences and non-coding sequences.
CpG dinucleotide frequencies in coding DNA sequences and non-coding sequences.
Mohita Upadhyay (698237) +1 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Quantitative sequence and open reading frame analysis based on codon bias [PDF]
The frequencies with which the sixty-four codons occur in human coding DNA are known. If we assume that the codons occur randomly, subject only to these probabilities, then it is possible to predict trinucleotide frequencies in each of the five other ...
Susan Rainey, Joe Repka
doaj
Functions of human non-coding dna sequences [PDF]
The development of string theory has opened a completely new chapter and the way of thinking. A tight connection between DNA, water and strings, as well as their properties, lead to the idea that the soul is the shelter of our thoughts. Only 2% of the
Stupar Milanko +2 more
doaj +1 more source

