Results 61 to 70 of about 2,863,112 (293)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Color Image Encryption Algorithm Based on Chaotic System and Dynamic DNA Coding and Operation [PDF]

open access: yesJisuanji gongcheng, 2018
Aiming at the problem that the chaos based image encryption algorithm combined with DNA coding can be broken caused by incorrect use of DNA coding rules and calculation methods,a new image encryption algorithm combined Intertwining Logistic mapping and ...
YANG Jiyun,WU Hao
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Application of Machine Learning to Environmental DNA Metabarcoding

open access: yesIEEE Access, 2022
Machine learning is known as an effective technique to classify big data, and coding methods for input into neural networks are critical. In this study, we have applied the machine learning to environmental deoxyribonucleic acid (DNA) metabarcoding.
Mutsumi Kimura   +2 more
doaj   +1 more source

Linear constructions for DNA codes

open access: yesTheoretical Computer Science, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gaborit, Philippe, King, Olivier D.
openaire   +2 more sources

CpG dinucleotide frequencies in coding DNA sequences and non-coding sequences.

open access: yes, 2015
CpG dinucleotide frequencies in coding DNA sequences and non-coding sequences.
Mohita Upadhyay (698237)   +1 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Quantitative sequence and open reading frame analysis based on codon bias [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2006
The frequencies with which the sixty-four codons occur in human coding DNA are known. If we assume that the codons occur randomly, subject only to these probabilities, then it is possible to predict trinucleotide frequencies in each of the five other ...
Susan Rainey, Joe Repka
doaj  

Functions of human non-coding dna sequences [PDF]

open access: yesArchive of Oncology, 2011
The development of string theory has opened a completely new chapter and the way of thinking. A tight connection between DNA, water and strings, as well as their properties, lead to the idea that the soul is the shelter of our thoughts. Only 2% of the
Stupar Milanko   +2 more
doaj   +1 more source

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