Results 171 to 180 of about 108,714 (328)

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic

open access: yesSmall, EarlyView.
Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi   +11 more
wiley   +1 more source

Optimizing Droplet Digital PCR Assay for Precise Assessment of MEIS1 Gene Promoter Methylation

open access: yesActa Medica Martiniana
DNA methylation is characterized as a gene regulatory mechanism that involves the methylation of the 5-carbon (C5) position of cytosine, resulting in the formation of 5-methylcytosine. The analysis of aberrantly methylated cytosine-phosphate-guanine (CpG)
Marek Samec   +5 more
doaj   +1 more source

Advancing Single‐Walled Carbon Nanotubes toward Next‐Generation Electronic Materials: The Critical Roles of Purity and Processability

open access: yesSmall Methods, EarlyView.
Single‐walled carbon nanotubes (SWNTs) are promising for a wide range of applications. In particular, their exceptional electrical conductivity positions them as potential alternatives to traditional metal conductors. This review identifies the key mechanisms governing their conductivity within composites and proposes practical pathways for translating
Xiao Yu, Alex Adronov
wiley   +1 more source

Quantizing DNA Metallization for Site‐Defined Growth of Single Quantum Emitters

open access: yesSmall Structures, EarlyView.
Predictive design rules guide DNA origami‐templated synthesis of atomically precise silver nanoclusters. Controlled nucleation yields single emitters with nanometer registration and reproducible fluorescence signatures, paving the way toward programable quantum photonic architectures and nanoscale device integration.
Swati Tanwar   +6 more
wiley   +1 more source

The shibirets4 mutation causes temperature sensitive paralytic and lethal phenotypes in the Queensland fruit fly, Bactrocera tryoni

open access: yesInsect Science, EarlyView.
Abstract Bactrocera tryoni, the Queensland fruit fly, is among the most damaging insect pests to the Australian horticultural industry as larvae infest ripening fruits or vegetables prior to harvest. Genetic biocontrol using Sterile Insect Technique (SIT) programs have been used to successfully suppress populations, via mass release of factory‐reared ...
Anzu Okada   +7 more
wiley   +1 more source

An oligodeoxyribonucleotide containing 5-formyl-2'-deoxycytidine (fC) at the CpG site forms a covalent complex with DNA cytosine-5 methyltransferases (DNMTs).

open access: yesBioorganic & Medicinal Chemistry Letters, 2016
Kousuke Sato   +4 more
semanticscholar   +1 more source

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