Results 271 to 280 of about 108,714 (328)

Research progress of base editing and prime editing tools based on the CRISPR/Cas system. [PDF]

Mol Ther Nucleic Acids
Gao H, Gao S, Kan G, Valentovich LN, An Y.   +4 more
europepmc   +1 more source

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, Volume 4, Issue 2, February 2026.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source

Base editing both DNA strands in distinct editing windows with small CRISPR-associated effector Cas12f1. [PDF]

iScience
Swartjes T, Bouzetos E, Adiego-Pérez B, Pool VD, Staals RHJ, van der Oost J, Wu WY.   +6 more
europepmc   +1 more source

Phylogenetic Analysis of Tanypodinae (Chironomidae, Diptera) Infered From Whole Mitochondrial Genomes

Ecology and Evolution, Volume 16, Issue 2, February 2026.
We generated the inaugural full mitogenomic sequences for 22 Tanypodinae taxa, and the mitochondrial genome sequence of another individual of Thienemannimyia tripunctata has been added; merged these novel records with previously released chironomid mitochondrial genomes; and performed an integrated comparative mitogenomic survey encompassing 55 ...
Wen‐Bin Liu, Jia‐Xin Nie, Ya‐Ning Tang, Zi‐Ming Shao, Cheng‐Yan Wang, Chun‐Cai Yan   +5 more
wiley   +1 more source

Macroid Formation in Salmacina stellaebayensis n. sp. From Mauritania's Baie de l'Étoile With New Insights on Mitogenome Evolution in Serpulidae (Annelida)

Ecology and Evolution, Volume 16, Issue 2, February 2026.
We describe Salmacina stellaebayensis n. sp. from Mauritania's Baie de l'Étoile and provide the first complete mitochondrial genome for the genus Salmacina. The species forms distinctive macroid colonies in Cymodocea nodosa seagrass meadows, offering new insights into serpulid life history and habitat specialization.
Hannah A. Cremer, Elena Kupriyanova, Alexander H. Knorrn, Sidi M. M. Moctar, Andre Freiwald, Ekin Tilic   +5 more
wiley   +1 more source

High-efficiency base editing for nuclear and mitochondrial DNA with an optimized DYW-like deaminase. [PDF]

Mol Ther
Kweon J, Park S, Jeon MY, Lim K, Jang G, Jang AH, Lee M, Seok C, Lee C, Park S, Ahn J, Jang J, Kim N, Sung YH, Kim D, Kim Y.   +15 more
europepmc   +1 more source

Chronic Granulomatous Disease: Clinical and Molecular Characterization of Brazilian Patients

The Journal of Gene Medicine, Volume 28, Issue 2, February 2026.
Chronic granulomatous disease is a rare inborn error of immunity characterized by the deficient production of reactive oxygen species in phagocytes, which are used in pathogen elimination. Affected individuals become susceptible to severe infections.
Leonardo Martinello da Rosa, Martha Braun da Rosa, Mariana de Sampaio Leite Jobim Wilson, Ida Vanessa Doederlein Schwartz, Fernanda Sperb‐Ludwig   +4 more
wiley   +1 more source

Indirect identification of genomic G-quadruplexes via a small protein probe that specifically recognizes C-rich single-stranded DNA. [PDF]

Nucleic Acids Res
Chen JN, Xie ML, Yan JY, Cai TT, Ding YW, He TX, Wang J, Huang J, Zheng KW.   +8 more
europepmc   +1 more source

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

Nano Select, Volume 7, Issue 2, February 2026.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source