Results 241 to 250 of about 1,589,396 (359)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

UCHL3: a crucial deubiquitinase in DNA damage repair and tumor progression. [PDF]

Cancer Cell Int
Liu J, Hu S, Xiao J, Zhou J.
europepmc   +1 more source

Physical association of pyrimidine dimer DNA glycosylase and apurinic/apyrimidinic DNA endonuclease essential for repair of ultraviolet-damaged DNA.

, 1981
Yusaku Nakabeppu, Masahiro Sekiguchi
openalex   +1 more source

Nitroaromatic radiation sensitizers substitute for oxygen in neocarzinostatin-induced DNA damage. [PDF]

, 1984
Lizzy S. Kappen, I. Goldberg
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Growth arrest is a DNA damage protection strategy in Arabidopsis. [PDF]

Nat Commun
Serrano-Mislata A, Hernández-García J, de Ollas C, Blanco-Touriñán N, Jurado-García S, Úrbez C, Gómez-Cadenas A, Sablowski R, Alabadí D, Blázquez MA.   +9 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Differential effects of mercury compounds on mutagenicity, genotoxicity and repair of UV-DNA damage. [PDF]

Toxicology
Cyran A, Ursu GM, Krawic C, Zhitkovich A.   +3 more
europepmc   +1 more source

In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by gamma-irradiation.

, 1985
Christopher J. Chetsanga, Cheryl Grigorian   +1 more
openalex   +1 more source

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source