Results 221 to 230 of about 976,559 (349)

CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion.

Cancer Research, 2018
X. Jiao, M. Velasco-Velázquez, Min Wang, Zhiping Li, H. Rui, Amy R. Peck, J. Korkola, Xue-lian Chen, Shaohua Xu, J. DuHadaway, S. Guerrero-Rodríguez, S. Addya, Daniela Sicoli, Z. Mu, Gang Zhang, A. Stucky, Xi Zhang, M. Cristofanilli, A. Fatatis, J. Gray, J. Zhong, G. Prendergast, R. Pestell   +22 more
semanticscholar   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Investigation of radiation-induced DNA damage repair-related genes as diagnostic biomarkers for radiation. [PDF]

J Radiat Res
Zhang Q, Yu Y.
europepmc   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

UCHL3: a crucial deubiquitinase in DNA damage repair and tumor progression. [PDF]

Cancer Cell Int
Liu J, Hu S, Xiao J, Zhou J.
europepmc   +1 more source

Functions of PARylation in DNA Damage Repair Pathways

Genomics, Proteomics & Bioinformatics, 2016
Huiting Wei, Xiaochun Yu
semanticscholar   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

IGF1R promotes radiation-induced HSCs activation by regulating DNA-PKcs-mediated DNA damage repair. [PDF]

Front Cell Dev Biol
Lin J, Zhao G, Feng J, Sun C, Liu C, Li J, Shen Y, Cheng Y.   +7 more
europepmc   +1 more source

Oxidative DNA damage & repair: An introduction.

Free Radical Biology & Medicine, 2017
J. Cadet, K. Davies
semanticscholar   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source