Results 281 to 290 of about 377,653 (310)

Repair of DNA damage in mitochondria

Mutation Research/DNA Repair, 1999
D E, Sawyer, B, Van Houten
openaire   +2 more sources

Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens

Nature Reviews Molecular Cell Biology, 2023
Stephen P Jackson, Jackson Stephen P
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REPAIRABLE DAMAGE IN DNA

1978
ABSTRACT Important contributions to the elucidation of the role of DNA repair for cell viability, mutagenesis, malignant transformation and cell degeneration are expected from experiments in which individual DNA lesions of known chemical structure are investigated.
openaire   +1 more source

DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies

Human Reproduction Update, 2022
Richard Musson, Łukasz Gąsior, Simona Bisogno   +2 more
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DNA Damage Repair

2017
DNA damage, when occurring in cancer-related genes, may lead to tumorigenesis. In normal cells, such DNA alterations activate a complex machinery of DNA damage repair. Genomic defects in DNA damage repair genes are known to be major drivers of cancer development and progression, in particular in breast and colon cancer.
openaire   +1 more source

Minimizing the damage: repair pathways keep mitochondrial DNA intact

Nature Reviews Molecular Cell Biology, 2012
Lawrence Kazak, Aurelio Reyes, Ian J Holt   +2 more
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DNA Damage/Repair Management in Cancers

Cancers, 2020
Jehad F Alhmoud, John F Woolley, Ala-Eddin Al Moustafa   +2 more
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Balancing repair and tolerance of DNA damage caused by alkylating agents

Nature Reviews Cancer, 2012
Jennifer A Calvo, Leona D Samson, Samson Leona D   +2 more
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The Nobel Prize 2015: The year of DNA repair

Nature Reviews Molecular Cell Biology, 2015
Kim Baumann, Baumann Kim
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Mutational signatures are jointly shaped by DNA damage and repair

Nature Communications, 2020
Naděžda V Volkova, Bettina Meier, VÍCTOR Gonzalez-Huici   +2 more
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