Results 291 to 300 of about 976,559 (349)

Knowledge mapping of global trends in DNA damage repair-related breast cancer research: a bibliometric study. [PDF]

Front Oncol
Huang Y, Wei S, Hu K, Xiang X.
europepmc   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

NSUN5 Mediates Resistance to Doxorubicin via Up-regulation of DNA Damage Repair Proteins BRCA2 and BRIP1 in Colorectal Cancer. [PDF]

Am J Pathol
Xu Y, Qin C, Zhang M, Wu Q, Li Z, Mo H, Chen C, Zhou A, Li J, Ni W.   +9 more
europepmc   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Arsenic enhances cervical cancer cell radiosensitivity by suppressing the DNA damage repair pathway. [PDF]

Transl Cancer Res
Gao X, Liu G, Zhao Z, Tang Y, Hui H, Wang C, Li D, Ma Y, Sun Z, Zhou Y.   +9 more
europepmc   +1 more source

USP5-Rich Apoptotic Extracellular Vesicles Regulate Nucleus Pulposus Cells Apoptosis and DNA Damage Repair by Preventing E2F1 Proteasomal Degradation. [PDF]

J Extracell Vesicles
Shi P, Gao H, Cheng Z, Wu W, Zhang A, Chen X, Wu W, Zhang Y.   +7 more
europepmc   +1 more source

DNA Damage Repair in Glioblastoma: A Novel Approach to Combat Drug Resistance. [PDF]

Cell Prolif
Gaiaschi L, Casali C, Stabile A, D'Amico S, Ravera M, Gabano E, Galluzzo A, Favaron C, Gola F, De Luca F, Pellegatta S, Bottone MG.   +11 more
europepmc   +1 more source

Olaparib and Durvalumab in Patients with DNA Damage Repair Alterations and Biochemically Recurrent Prostate Cancer. [PDF]

J Immunother Precis Oncol
Autio KA, McHugh DJ, Rathkopf DE, Xiao H, Merugu S, Wong P, Jan M, Dorff TB, Heath EI, Scher HI.   +9 more
europepmc   +1 more source

Impact of glycolysis enzymes and metabolites in regulating DNA damage repair in tumorigenesis and therapy. [PDF]

Cell Commun Signal
Sun F, Li W, Du R, Liu M, Cheng Y, Ma J, Yan S.   +6 more
europepmc   +1 more source

Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide. [PDF]

Neuro Oncol
Guerra G, Wendt G, McCoy L, Hansen HM, Kachuri L, Molinaro AM, Rice T, Guan V, Capistrano L, Hsieh A, Kalsi V, Sallee J, Taylor JW, Clarke JL, Almaraz ER, Wiencke JK, Eckel-Passow JE, Jenkins RB, Wrensch M, Francis SS.   +19 more
europepmc   +1 more source