Results 301 to 310 of about 976,559 (349)

Ultrarare Variants in DNA Damage Repair and Mitochondrial Genes in Pediatric Acute-Onset Neuropsychiatric Syndrome and Acute Behavioral Regression in Neurodevelopmental Disorders

Vettiatil D, Soorajkumar A, Dubin RA, Pedrosa E, Schornagel A, Lambert JS, Costa IP, McDonald J, Swagemakers SM, van der Spek PJ, Frankovich J, Cunningham JL, Lachman HM.   +12 more
europepmc   +1 more source

Exercise serum promotes DNA damage repair and upregulates DNA repair genePNKPin colon cancer cells

Orange ST, Dodd E, Nath S, Bowden H, Jordan A, Smith H, Hedley A, Chukwuma I, Hickson I, Saha SS.   +9 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Repairing DNA-methylation damage

Nature Reviews Molecular Cell Biology, 2004
Methylating agents modify DNA at many different sites, thereby producing lethal and mutagenic lesions. To remove all the main harmful base lesions, at least three types of DNA-repair activities can be used, each of which involves a different reaction mechanism.
openaire   +2 more sources

Cohesin and DNA damage repair

Experimental Cell Research, 2006
Replicated DNA molecules are physically connected by cohesin complexes from the time of their synthesis in S-phase until they are segregated during anaphase of the subsequent mitosis or meiosis. This sister chromatid cohesion is essential for the biorientation of chromosomes on the mitotic or meiotic spindle.
Erwan, Watrin, Jan-Michael, Peters
openaire   +2 more sources

DNA damage, repair and chromosomal damage

International Journal of Radiation Biology, 1997
An important question in radiobiology is the relationship between primary DNA damage and chromosomal aberrations. What determines the chromosomal aberration frequency, especially in radiosensitive cells? Much evidence points to the double-strand break (dsb) as the critical lesion, however there is controversy over whether it is the initial induction ...
openaire   +2 more sources

DNA Damage and Repair

1991
Some of the background to radiation chemical studies of DNA damage is presented, followed by a review of measurements of such damage and its repair in mammalian cells. While most effort has been placed on the measurement of radiation-induced strand breaks (because assays can be used in the biologically relevant dose range), the radiation-altered bases ...
openaire   +3 more sources

Patients Resistant Against PSMA-Targeting α-Radiation Therapy Often Harbor Mutations in DNA Damage-Repair–Associated Genes

Journal of Nuclear Medicine, 2019
Prostate-specific membrane antigen (PSMA)–targeting α-radiation therapy (TAT) is an emerging treatment modality for metastatic castration-resistant prostate cancer.
C. Kratochwil, F. Giesel, C. Heussel, Daniel Kazdal, V. Endris, Cathleen Nientiedt, F. Bruchertseifer, Maximilian Kippenberger, H. Rathke, J. Leichsenring, M. Hohenfellner, A. Morgenstern, U. Haberkorn, S. Duensing, A. Stenzinger   +14 more
semanticscholar   +1 more source

Chromatin and DNA damage repair

Russian Journal of Genetics, 2011
In eukaryotic cells, inheritance of both exact DNA sequence and its arrangement into the chromatin is critical for maintaining stability of the genome. Various DNA lesions induced by endogenous and exogenous factors make this maintenance problematic. To understand completely how cells resolve this problem the knowledge on the nature of these lesions ...
openaire   +2 more sources

Plant DNA-damage repair/toleration 100 protein repairs UV-B-induced DNA damage

DNA Repair, 2014
We report the characterization of VvDRT100-L, a grape DNA-damage repair/toleration 100 protein. VvDRT100-L has nine leucine-rich repeats and belongs to the plant DRT100 protein family. VvDRT100-L is expressed abundantly in green organs of grapevines, including tendrils, leaves, and green berry skins.
Nozomi Fujimori, Nana Suzuki, Yuko Nakajima, Shunji Suzuki   +3 more
openaire   +2 more sources

Repairable Damage in DNA: Overview

1975
Due to the central functional role of DNA and the fact that each cell contains only one or at the most a few copies of each chromosome, damage to DNA has more severe implications for the functional integrity of the cell than does damage to most other cellular components.
openaire   +2 more sources