Results 141 to 150 of about 60,468 (238)

A Nanoparticle-Based Strategy to Stabilize 5-Azacytidine and Preserve DNA Demethylation Activity in Human Cardiac Fibroblasts. [PDF]

Pharmaceutics
Kheawfu K, Chittasupho C, Singh S, Okonogi S, Karuna N.   +4 more
europepmc   +1 more source

The Effect of CYP1A2 Gene Polymorphisms on Caffeine Pharmacokinetics and Exercise Performance in Male Recreational Athletes

European Journal of Sport Science, Volume 26, Issue 7, July 2026.
ABSTRACT This study examined the effects of caffeine consumption on endurance exercise performance, and the influence of CYP1A2 gene polymorphisms in caffeine pharmacokinetics and exercise performance. The data sets of two randomised, double blind, placebo‐controlled crossover study design experiments have been merged.
Chloe Masters, Ajmol Ali, Claire Badenhorst, Martin Dickens, Kay Rutherfurd‐Markwick   +4 more
wiley   +1 more source

Loss of TET2 activity limits the ability of vitamin C to activate DNA demethylation in human HAP1 cells. [PDF]

Epigenetics Chromatin
Gawronski M, Starczak M, Wasilow A, Dziaman T, Olinski R, Gackowski D.   +5 more
europepmc   +1 more source

Directing DNA demethylation [PDF]

Nature Structural & Molecular Biology, 2013
openaire   +1 more source

Antifungal Potential of Cumin Spice Seeds, Cuminum cyminum, Against Aspergillus fumigatus: Mechanistic Insights Into Ergosterol, Melanin, and Biofilm Inhibition

Food Frontiers, Volume 7, Issue 4, July 2026.
Antifungal effects and underlying mechanism of the action of the supercritical fluid extracted from the cumin (Cuminum cyminum) seeds and its volatile phyto‐constituents against pathogenic Aspergillus fumigatus. ABSTRACT Spices are aromatic culinary ingredients used worldwide for enhancing food flavors, folklore therapy, and their antiseptic ...
Acharya Balkrishna, Lovely Gupta, Rani Singh, Yash Varshney, Rishabh Dev, Pardeep Nain, Savita Lochab, Anurag Varshney   +7 more
wiley   +1 more source

Tet3-mediated DNA demethylation is essential for maintaining the dedifferentiation capacity of mammalian Müller glia. [PDF]

Front Mol Neurosci
Martinez-Colin EJ, Lezama I, Ochoa-de la Paz LD, Lamas M.   +3 more
europepmc   +1 more source

PKMYT1 in Cancer: Beyond Cell Cycle Checkpoints to Context‐Dependent Therapeutic Vulnerability

Genes, Chromosomes and Cancer, Volume 65, Issue 7, July 2026.
ABSTRACT PKMYT1 has emerged as a promising therapeutic target distinguished by its tumor‐selective expression and essential role in replication stress management. Unlike WEE1, PKMYT1 is dispensable in normal cell cycles but critical for cancer cells coping with DNA damage, establishing a broad therapeutic window.
Lingxi Li, Binfan He, Mengmeng Hao, Ye Liu, Shunxin Song, Rongzhang He   +5 more
wiley   +1 more source

Lessons From Astaxanthin Therapy to Combat Oral Premalignant and Malignant Lesions: A Narrative Review

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Oral cancer is one of the most common head and neck malignancies and remains associated with high morbidity, mortality, and treatment‐related toxicity. Despite advances in surgery, radiotherapy, and chemotherapy, there is still a need for safer adjunctive therapies with better therapeutic potential.
Reza Arefnezhad, Zhina Mohamadi, Shervin Shahianjahromi, Amirali Fallahian, Maryam Ashrafi, Armin Nikdehqan, Mitra Saeedi Valashani, Reza Nasiri, Fatemeh Zeinali, Hossein Fatemian, Niloofar Sefati, Fatemeh Rezaei‐Tazangi, Marziye Ranjbar Tavakoli   +12 more
wiley   +1 more source

Ten-eleven translocation 2-mediated DNA demethylation plays a positive regulatory role in BMP9-induced osteogenic differentiation of mesenchymal stem cells. [PDF]

Genes Dis
Chen C, Zhu Y, Zhao S, Xiang M, Yu C, Peng Y, Liang Y, Baek J, Qiao L, Dong X, Yao F, Huang J, He TC, Reid RR, Fan J, Schimizzi G, Bougioukli S, Xu Y, Luo C.   +18 more
europepmc   +1 more source

Primary productivity coupled to oxic methane production in coastal waters of southern China

Limnology and Oceanography Letters, Volume 11, Issue 4, July 2026.
Abstract Oxic methane (CH4) production (OMP) occurs in diverse oxygenated surface waters worldwide. However, phytoplankton‐driven OMP in natural marine environments remains poorly documented. During a research cruise in the highly productive southern East China Sea, we measured OMP by incubating phytoplankton‐rich surface waters and found that CH4 ...
Yuming Rao, Guang Gao, Mina Bizic, Ilana Berman‐Frank, Kunshan Gao   +4 more
wiley   +1 more source