Results 151 to 160 of about 60,603 (249)

In ovo sericin suppresses hepatic DNA demethylation in broilers at hatch. [PDF]

Poult Sci
Gupta V, Bhattacharyya A, Hwang YJ, Choi YH.   +3 more
europepmc   +1 more source

DNA Demethylation In Vitro [PDF]

Cell, 1998
openaire   +1 more source

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

β-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration. [PDF]

Adv Sci (Weinh)
Kong X, Gu H, Zhang Y, Meng Q, Li Q, Song K, Li Y, Liu K, Liu Z, Hu R, Zhai H, Li T, Ling Z, Wei Z, Wei F, Cheng L.   +15 more
europepmc   +1 more source

Loss of DNA methylation is not associated with venetoclax–hypomethylating agents synergy in acute myeloid leukaemia cells

British Journal of Haematology, EarlyView.
Aida Selimović‐Pašić, Lisa Haglund, Maike Bensberg, Júlia Goldmann, Padraig D'arcy, Sandra Hellberg, Colm E. Nestor   +6 more
wiley   +1 more source

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

The FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe, Ricardo Alva, Fereshteh Moradi, Sarah Alderman, Ping Liang, Jeffrey A. Stuart   +5 more
wiley   +1 more source

Dual DNA demethylation mechanisms implement epigenetic memory driven by the pioneer factor PAX7. [PDF]

Sci Adv
Harris J, Mayran A, Gouhier A, Gauthier Y, Sleiman NH, Merabet S, Dukatz M, Bashtrykov P, Jeltsch A, Djambazian H, Chen SH, Balsalobre A, Drouin J.   +12 more
europepmc   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

PROSER1 modulates DNA demethylation through dual mechanisms to prevent syndromic developmental malformations. [PDF]

Genes Dev
Fleming A, Knatko EV, Li X, Zoch A, Heckhausen Z, Stransky S, Brenes AJ, Sidoli S, Hajkova P, O'Carroll D, Rasmussen KD.   +10 more
europepmc   +2 more sources

CCNY-mediated phosphorylation and TET2-BACH1-driven DNA demethylation activate PRC1 to augment NSCLC progression. [PDF]

J Exp Clin Cancer Res
Huang D, Chu X, Wu C, Wang X, Shi M, Chen X, Lyu Y, Li D, Gu X.   +8 more
europepmc   +1 more source