Epigenetic Regulation in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch +3 more
wiley +1 more source
Transposition element MERVL regulates DNA demethylation through TET3 in oxidative-damaged mouse preimplantation embryos. [PDF]
Mol MedLiu L, Ha S, Cao D, Li M, Li Z.
europepmc +1 more source
New Phytologist, EarlyView.Species‐level variation in temperate tree foliar greenhouse gas exchange, showing consistent foliar CH4 uptake, N2O emission, stronger CH4 uptake in fall leaves, and contrasting methanotroph communities between the high‐CH4‐oxidizing species Tilia americana and the low‐CH4‐oxidizing species Prunus virginiana. Summary The contribution of tree foliage to
Md Rezaul Karim, Sean C. Thomas
wiley +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
Oral Diseases, EarlyView.ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
Plant, Cell &Environment, EarlyView.ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.This study evaluated the photodegradation of commercial insect repellents containing DEET and IR‐3535 under UV‐A and UV‐B irradiation using Raman spectroscopy. Pure DEET and IR‐3535 showed intrinsic photostability, whereas DEET diluted in ethanol and a commercial DEET‐based formulation exhibited significant spectral changes after UV exposure.
Viviane Gadret Borio +4 more
wiley +1 more source
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide. [PDF]
Nat Struct Mol BiolSepulveda H +20 more
europepmc +1 more source
Understanding exosomes in regenerative dentistry
Periodontology 2000, EarlyView.Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
Association Between Active DNA Demethylation and Liver Fibrosis in Individuals with Metabolic-Associated Steatotic Liver Disease (MASLD). [PDF]
Int J Mol SciBarchetta I +11 more
europepmc +1 more source