Results 171 to 180 of about 60,468 (238)

Multiaxial Biophysical Control of Oncogenic Phase Separation by Indoleamines: A Proof‐of‐Concept Synthesis of Landscape‐Level Regulation

Journal of Pineal Research, Volume 78, Issue 4, July 2026.
ABSTRACT Oncogenic condensates act as biophysical sanctuaries that stabilize malignant survival programs. However, a universal regulator capable of orchestrating the integrated biophysical axes governing cellular phase behavior has remained elusive.
Doris Loh, Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter   +3 more
wiley   +1 more source

Transposition element MERVL regulates DNA demethylation through TET3 in oxidative-damaged mouse preimplantation embryos. [PDF]

Mol Med
Liu L, Ha S, Cao D, Li M, Li Z.
europepmc   +1 more source

StALKBH10B‐Mediated RNA m6A Modification Inhibits Potato Salt Tolerance by Targeting Flavonoids and ABA Signalling Pathways

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4435-4453, July 2026.
ABSTRACT N6‐methyladenosine (m6A) is the most prevalent methylation modification present in mRNAs, which has been confirmed to participate in many developmental and biological processes. However, the biological function and specific regulatory mechanism of m6A modification in relation to salt tolerance of potato remain obscure.
Xuanming Dong, Jianyu Ma, Chenxin Sui, Yan Li, Vadim Khassanov, Hongju Jian, Dianqiu Lv   +6 more
wiley   +1 more source

Structural Elucidation and Engineering of the (S)‐scoulerine 2‐O‐Methyltransferase Enabling Regioselective Epiberberine Biosynthesis in Coptis chinensis

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4528-4545, July 2026.
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song, Di Liu, Shi Chen, Yufeng Tan, Siyu Wang, Shihan Li, Yutong Qin, Guofeng Li, Xufang Tian, Lan Yang, Chong Yuan, Junbo Gou, Wei Huang, Shilin Chen, Yifei Liu   +14 more
wiley   +1 more source

DNA Hypomethylation Is One of the Epigenetic Mechanisms Involved in Salt‐Stress Priming in Soybean Seedlings

Plant, Cell &Environment, Volume 49, Issue 7, Page 3764-3776, July 2026.
ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung, Qianwen Wang, Long‐Yiu Chan, Zhili Wang, Mingkun Huang, Man‐Wah Li, Fuk‐Ling Wong, Hon‐Ming Lam   +7 more
wiley   +1 more source

In Vitro SDHI Fungicide Insensitivity and Mutations in Sdh, β‐Tubulin and Cyp51 of Clarireedia spp., Causing Dollar Spot in Turfgrass in Georgia, USA

Plant Pathology, Volume 75, Issue 4, July‐August 2026.
Amino acid substitutions R61K and E63A in SdhD gene and E198A in β‐tubulin gene in Clarireedia spp., causal agent of dollar spot in turfgrass, were linked to reduced boscalid and thiophanate‐methyl sensitivity, respectively. ABSTRACT Dollar spot, caused by Clarireedia spp., diminishes turf quality, affecting both aesthetics and sport playability on the
Md. Aktaruzzaman, Bikash Ghimire, Harshita Saxena, Moumita Majumdar, Jonathan E. Oliver, James W. Buck, Alfredo D. Martinez‐Espinoza, Bochra A. Bahri   +7 more
wiley   +1 more source

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide. [PDF]

Nat Struct Mol Biol
Sepulveda H, Li X, Arteaga-Vazquez LJ, López-Moyado IF, Brunelli M, Hernández-Espinosa L, Yue X, Angel JC, Brown C, Dong Z, Jansz N, Puddu F, Modat A, Scotcher J, Creed P, Kennedy PH, Manriquez-Rodriguez C, Myers SA, Crawford R, Faulkner GJ, Rao A.   +20 more
europepmc   +1 more source

Synthesis of Aromatic Aldehydes by CH Formylation of Aromatics with Silyl Formates Prepared from CO2 and Hydrosilanes

Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
A new method has been developed for the C–H formylation of aromatic compounds using silyl formates synthesized from CO2 and hydrosilanes. This is the first report on the direct C–H formylation of aromatics with silyl formates. The formylation reactions were promoted by BBr3 or BCl3. The reaction mechanism has been clarified by DFT calculations. Despite
Natsumi Nitta, Kei Hirokawa, So Saibara, Bikash Dev Nath, Kazuto Takaishi, Tadashi Ema   +5 more
wiley   +1 more source

DNA demethylation mediated endogenous retroviruses transcription promotes aberrant T cell differentiation in systemic lupus erythematosus via RIG-I pathway. [PDF]

EBioMedicine
Min X, Yu Y, Hu Z, Ouyang L, Qiu Y, Zhao H, Wu J, Zou C, Zheng M, Yang S, Jia S, Yu D, Lu Q, Zhao M.   +13 more
europepmc   +1 more source