Results 191 to 200 of about 60,468 (238)

Primordial germ cell DNA demethylation and development require DNA translesion synthesis. [PDF]

Nat Commun
Shah P, Hill R, Dion C, Clark SJ, Abakir A, Willems J, Arends MJ, Garaycoechea JI, Leitch HG, Reik W, Reik W, Crossan GP.   +11 more
europepmc   +1 more source

Divergent MYB paralogs determine spatial distribution of linalool mediated by JA and DNA demethylation participating in aroma formation and cold tolerance of tea plants. [PDF]

Plant Biotechnol J
Yue R, Li Y, Qi Y, Liang X, Zheng Z, Ye Z, Tong W, Si X, Zhang Y, Xia E, Li P.   +10 more
europepmc   +1 more source

Genome-wide characterization of dynamic DNA 5-hydroxymethylcytosine and TET2-related DNA demethylation during breast tumorigenesis. [PDF]

Clin Epigenetics
Wu SL, Yang L, Huang C, Li Q, Ma C, Yuan F, Zhou Y, Wang X, Tong WM, Niu Y, Jin F.   +10 more
europepmc   +1 more source

DNA demethylation in the hypothalamus promotes transcription of Agtr1a and Slc12a2 and hypertension development. [PDF]

J Biol Chem
Ghosh K, Zhou JJ, Shao JY, Chen SR, Pan HL.   +4 more
europepmc   +1 more source

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD.

Blood
Zaiken MC, Jin S, McDonald-Hyman CS, Hartigan CR, Sage PT, Hippen KL, Koehn BH, Panoskaltsis-Mortari A, Riddle MJ, Eide CR, Tolar J, Hill GR, Luznik L, Cutler CS, Ritz JR, Kean LS, Tsagaratou A, Rao A, Blazar BR.   +18 more
europepmc   +1 more source

Distinct Regions within SAP25 Recruit O-Linked Glycosylation, DNA Demethylation, and Ubiquitin Ligase and Hydrolase Activities to the Sin3/HDAC Complex. [PDF]

J Proteome Res
Goswami P, Banks CAS, Thornton J, Bengs BD, Sardiu ME, Florens L, Washburn MP.   +6 more
europepmc   +1 more source

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Active DNA demethylation and DNA repair

Differentiation, 2009
DNA methylation on cytosine is an epigenetic modification and is essential for gene regulation and genome stability in vertebrates. Traditionally DNA methylation was considered as the most stable of all heritable epigenetic marks. However, it has become clear that DNA methylation is reversible by enzymatic "active" DNA demethylation, with examples in ...
Christof Niehrs
exaly   +3 more sources

DNA Methylation and Demethylation in Plant Immunity

Annual Review of Phytopathology, 2016
Detection of plant and animal pathogens triggers a massive transcriptional reprogramming, which is directed by chromatin-based processes, and ultimately results in antimicrobial immunity. Although the implication of histone modifications in orchestrating biotic stress–induced transcriptional reprogramming has been well characterized, very little was ...
Luis Navarro
exaly   +4 more sources

Active DNA demethylation damages DNA

Science, 2022
Active DNA demethylation maintains enhancer activity in nonproliferating cells but can damage ...
Isaac F, López-Moyado, Anjana, Rao
openaire   +2 more sources

DNA Demethylation and Carcinogenesis

Biochemistry (Moscow), 2005
DNA methylation plays an important role in the establishment and maintenance of the program of gene expression. Tumor cells are characterized by a paradoxical alteration of DNA methylation pattern: global DNA demethylation and local hypermethylation of certain genes.
N P, Kisseljova, F L, Kisseljov
openaire   +2 more sources