Results 161 to 170 of about 60,468 (238)

PROSER1 modulates DNA demethylation through dual mechanisms to prevent syndromic developmental malformations. [PDF]

Genes Dev
Fleming A, Knatko EV, Li X, Zoch A, Heckhausen Z, Stransky S, Brenes AJ, Sidoli S, Hajkova P, O'Carroll D, Rasmussen KD.   +10 more
europepmc   +2 more sources

5-Hydroxymethylcytosine: Far Beyond the Intermediate of DNA Demethylation. [PDF]

Int J Mol Sci
Zheng K, Lyu Z, Chen J, Chen G.
europepmc   +1 more source

MAP17 Enhances Chemoresistance and Tumorigenicity of Glioblastoma‐Initiating Cells via the Canonical NF‐кB Pathway

Cancer Science, Volume 117, Issue 7, Page 1841-1851, July 2026.
MAP 17 is identified as highly expressed in TMZ‐resistant glioblastoma‐initiating cells (GICs). MAP17 enhances GIC proliferation, TMZ resistance, and tumorigenicity through NF‐κB/RELA‐dependent BCL2 upregulation. ABSTRACT Glioblastoma (GBM) is the most common malignant brain tumor in adults.
Shenshen Dou, You Lee Son, Toru Kondo
wiley   +1 more source

Anticancer effects of zinc ion-mediated DNA demethylation in oesophageal squamous cell carcinoma. [PDF]

Front Pharmacol
Zhou B, Wang C, Huang Y, Yang X, Ye T, Shen L, Lv Q, Mao W, Zhao A.   +8 more
europepmc   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, Volume 178, Issue 3, Page 417-427, July 2026.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

TET1-mediated DNA demethylation suppresses migration of goat placental trophoblast cells. [PDF]

J Anim Sci
Sun Z, Tang Y, Liao Y, Ma X, Wang M, Fang X, Yang S, Zhao J, Zhao Y.   +8 more
europepmc   +1 more source

Practitioner Review: Infant mental health meets cell and molecular biology – a look to the future

Journal of Child Psychology and Psychiatry, Volume 67, Issue 7, Page 1190-1202, July 2026.
Background A major research effort in the past two decades has begun to illuminate how experience ‘gets under the skin’ – that is – the cellular and molecular processes that are associated with adversity and resilience. Methods We selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory
Charles H. Zeanah, Megan Hare, Katherine Cowhey, Stacy S. Drury   +3 more
wiley   +1 more source

Dimethyl sulfoxide-induced DNA demethylation during vitrification of early cleavage-stage embryos and possible countermeasures. [PDF]

J Assist Reprod Genet
Shida M, Ito J, Inoue Y, Hara S, Shirasuna K, Iwata H.   +5 more
europepmc   +1 more source

FcMAPK4‐phosphorylated FcNOR activates FcERF5 to promote fig fruit softening through activation of FcPG12 expression

Journal of Integrative Plant Biology, Volume 68, Issue 7, Page 2264-2284, July 2026.
In Ficus carica fruit, the MAP kinase FcMAPK4 phosphorylates the NAC transcription factor FcNOR, which cooperates with ethylene response factor FcERF5 to activate the pectin degradation gene FcPG12, thereby promoting rapid softening of fig fruit. ABSTRACT Rapid softening of fig (Ficus carica L.) fruit during ripening leads to extremely short shelf life;
Yuan Wang, Zhiyi Fan, Yining Wang, Alexander Vainstein, Yuexuan Qiu, Yinan Sun, Huiqin Ma   +6 more
wiley   +1 more source

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation. [PDF]

Nat Commun
Tan J, Li Y, Li X, Zhu X, Liu L, Huang H, Wei J, Wang H, Tian Y, Wang Z, Zhang Z, Zhu B.   +11 more
europepmc   +1 more source