Results 231 to 240 of about 96,036 (271)

Novel PMVs/ZIP4/Zinc/Prelamin A Axis Promotes Nuclear Dysmorphism and Vascular Aging in Humans and Rodents Post‐Injury: Effective Treatment With Platelet Membrane‐Coated ZIF‐8 Nanoparticles

Aging Cell, Volume 25, Issue 3, March 2026.
Interventional therapy and surgical injury induce nuclear dysmorphism and vascular aging. Nuclear dysmorphism is positively associated with vascular aging. Novel PMVs/ZIP4/Zinc/preLamin A axis plays a key role in injury‐induced nuclear dysmorphism and vascular aging.
Tengzhi Ma, Han Bao, Zhijue Xu, He Ren, Wenhao Tian, Jiahe Chen, Zhongqian Liu, Xinwu Lu, Fan Lv, Qingping Yao, Yingxin Qi, Kai Huang   +11 more
wiley   +1 more source

Divergent MYB paralogs determine spatial distribution of linalool mediated by JA and DNA demethylation participating in aroma formation and cold tolerance of tea plants. [PDF]

Plant Biotechnol J
Yue R, Li Y, Qi Y, Liang X, Zheng Z, Ye Z, Tong W, Si X, Zhang Y, Xia E, Li P.   +10 more
europepmc   +1 more source

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

The FEBS Journal, Volume 293, Issue 5, Page 1459-1477, March 2026.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver, Rachael Riley Denbrock, Cindy Carolina Martines, Alessandro Didonna   +3 more
wiley   +1 more source

miRNAs in Follicular and Oviductal Fluids Support Global DNA Demethylation in Early-Stage Embryos. [PDF]

Int J Mol Sci
Aoki S, Inoue Y, Hamazaki M, Hara S, Noguchi T, Shirasuna K, Iwata H.   +6 more
europepmc   +1 more source

Effects of Aerosol Extract From Heated Tobacco Products on Senescence‐Associated Gene Expression in Human Lung Fibroblasts

Geriatrics &Gerontology International, Volume 26, Issue 3, March 2026.
Repeated exposure to aerosols from heated tobacco products may affect senescence‐associated factors. ABSTRACT Aim Cellular senescence is associated with an increased risk of various diseases. Although heated tobacco products (HTPs) have become widespread substitutes for conventional combustible cigarettes, their role in cellular senescence remains ...
Ayami Sato, Satsuki Kasahara, Akihito Ishigami   +2 more
wiley   +1 more source

DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells. [PDF]

BMC Genomics
Toriyama K, Au Yeung WK, Inoue A, Kurimoto K, Yabuta Y, Saitou M, Nakamura T, Nakano T, Sasaki H.   +8 more
europepmc   +1 more source

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

Genome-wide characterization of dynamic DNA 5-hydroxymethylcytosine and TET2-related DNA demethylation during breast tumorigenesis. [PDF]

Clin Epigenetics
Wu SL, Yang L, Huang C, Li Q, Ma C, Yuan F, Zhou Y, Wang X, Tong WM, Niu Y, Jin F.   +10 more
europepmc   +1 more source

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

Transposable element‐mediated DNA methylation of the NAC20 and NAC26 promoters led to a maternal effect on grain filling

Journal of Integrative Plant Biology, Volume 68, Issue 3, Page 828-840, March 2026.
The rice transcription factor genes NAC20 and NAC26 regulate grain filling and show allele‐specific maternal expression due to transposable element insertions and paternal hypermethylation in their 5' upstream regions. Geographical analyses showed that japonica varieties that originated at high latitudes carried these transposable elements.
Ming‐Wei Wu, Rong Li, Wen‐Tao Wei, Meng‐Meng Chen, Jin‐Lei Liu, Han Cheng, Tao Yang, Jin‐Dan Zhang, Jinxin Liu, Chun‐Ming Liu   +9 more
wiley   +1 more source