Results 191 to 200 of about 846,282 (296)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

PowderBot: An automated device for decision-making in crop breeding programs based on DNA extraction from seed powder. [PDF]

HardwareX
Díaz H, Macea E, Escobar R, Beebe S, Tohme J, Raatz B.   +5 more
europepmc   +1 more source

Extraction of plasmid DNA using reactor scale alkaline lysis and selective precipitation for scalable transient transfection.

, 2001
Jason Wright, Martin Jordan, Florian Μ. Wurm   +2 more
openalex   +2 more sources

Use of Magnetic Beads for Plasma Cell-free DNA Extraction: Toward Automation of Plasma DNA Analysis for Molecular Diagnostics [PDF]

, 2003
Christine Stemmer, Michèle Beau‐Faller, Erwan Pencreach, Éric Guérin, Anne Schneider, Didier Jaqmin, Elizabeth Quoix, Marie‐Pierre Gaub, P Oudet   +8 more
openalex   +1 more source

DNA extraction protocol v1 [PDF]

, 2019
Unai Baroja, Inazio Garin, Joxerra Aihartza, Aitor Arrizabalaga-Escudero, Nerea Vallejo, Miren Aldasoro, Urtzi Goiti   +6 more
openaire   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

DNA extraction protocols for animal fecal material on blood spot cards. [PDF]

PLoS One
Llarena AK, Haverkamp THA, Gulliksen WS, Herstad K, Holst-Jensen A, Skjerve E, Rannem L, Rodriguez-Campos S, Øines Ø.   +8 more
europepmc   +1 more source

Incorporation of Sodium Sulfite into Extraction Protocol Minimizes Degradation of Acacia DNA

, 2001
Margaret Byrne, Bronwyn MacDonald, Michael G. Francki   +2 more
openalex   +1 more source

Evaluation of five DNA extraction methods for purification of DNA from atherosclerotic tissue and estimation of prevalence of Chlamydia pneumoniae in tissue from a Danish population undergoing vascular repair. [PDF]

, 2003
Tina Mygind, Lars Østergaard, Svend Birkelund, Jes S. Lindholt, Gunna Christiansen   +4 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source