Results 161 to 170 of about 222,504 (300)

Association of semen leukocytes with sperm DNA fragmentation in a clinical cohort. [PDF]

Front Endocrinol (Lausanne)
Peng L, Wang T, Zhu M, Le Y, Yang S.
europepmc   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Reconsidering the interpretation of sperm DNA fragmentation testing in ART decision-making. [PDF]

Hum Reprod Open
Esteves SC, Humaidan P.
europepmc   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Reply: Reconsidering the interpretation of sperm DNA fragmentation testing in ART decision-making. [PDF]

Hum Reprod Open
Wang Y, Wang R, Lian Y, Mol BW, Li R, Qiao J.   +5 more
europepmc   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Sperm Imprinted Gene Methylation and DNA Fragmentation in ICSI Outcomes: A Pilot Study. [PDF]

Epigenomes
Conflitti AC, Konstantinidou F, Buonacquisto A, Cicolani G, Delli Paoli E, Di Chiano S, Linari A, Muzii L, Bianchini S, Quaranta F, Pallotti F, Lombardo F, Stuppia L, Gatta V, Paoli D.   +14 more
europepmc   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Cell Death Associated with No Oligonucleosomal DNA Fragmentation

, 2003
P(論文)DNAのヌクレオソーム単位での断片化はアポトーシスの特徴的変化の一つであるが,断片化の欠損するアポトーシスも報告されている。本研究では,アポトーシスの核変化誘導機序の解明のために,DNA断片化を伴わない細胞死におけるその欠損原因の解析を行った。(1)ヌクレオソーム単位でのDNA断片化欠損はネオカルチノスタチンにより誘導されたMolt-4細胞のアポトーシスにおいて認められた。この時,DNA断片化に必須であるとされているDNA fragmentation factor (DFF)はMolt ...
ウスイ, シゲユキ, 17850, 平野, 和行, ヒラノ, カズユキ, 18099, HIRANO, Kazuyuki, 18100, 21242, 21241, 18101, 18095, 18096, USUI, Shigeyuki, 18097, 18092, 18093, イグチ, カズヒロ, 井口, 和弘, IGUCHI, Kazuhiro, イシダ, リョウジ, ISHIDA, Ryoji, 臼井, 茂之, 石田, 良司, 21240   +23 more
core  

The role of sperm DNA fragmentation testing in predicting IVF and PGT-A outcomes. [PDF]

Sci Rep
Okubo T, Kobayashi T, Hayashi T, Onda N, Omi K, Segawa T.   +5 more
europepmc   +1 more source