Results 131 to 140 of about 7,033 (174)

Repair of oxidatively induced DNA damage by DNA glycosylases: Mechanisms of action, substrate specificities and excision kinetics. [PDF]

Mutat Res Rev Mutat Res, 2017
Dizdaroglu M, Coskun E, Jaruga P.
europepmc   +1 more source

A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping. [PDF]

Nucleic Acids Res, 2018
Earl C, Bagnéris C, Zeman K, Cole A, Barrett T, Savva R.   +5 more
europepmc   +1 more source

The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure. [PDF]

Sci Rep, 2017
Martin PR, Couvé S, Zutterling C, Albelazi MS, Groisman R, Groisman R, Matkarimov BT, Parsons JL, Elder RH, Saparbaev MK.   +9 more
europepmc   +1 more source

Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation. [PDF]

Nat Struct Mol Biol, 2016
Schomacher L, Han D, Musheev MU, Arab K, Kienhöfer S, von Seggern A, Niehrs C.   +6 more
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Mechanisms of search for specific sites in DNA by DNA-binding proteins. [PDF]

Biochem Biophys Rep
Lukina MV, Fedorova OS, Chernonosov AA, Koval VV.   +3 more
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Facilitated DNA damage repair as an emerging therapeutic strategy for inflammatory and fibrotic diseases. [PDF]

RSC Chem Biol
Michel M, Taebnia N, Lauschke VM.
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Structural Basis for Nucleobase Activation by the Adenine DNA Glycosylase MutY. [PDF]

Chembiochem
Russelburg LP, Demir M, Cedeno K, David SS, Horvath MP.   +4 more
europepmc   +1 more source

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DNA glycosylases

Molecular and Cellular Biochemistry, 1982
Various DNA glycosylases exist, which initiate the first step in base-excision repair. A summary of the kinetic and physical characteristics of three classes of DNA glycosylases are presented here. The first class discussed, include glycosylases which recognize alkylated DNA.
S J, Caradonna, Y C, Cheng
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Structures and functions of DNA glycosylases

Mutation Research/DNA Repair, 1990
Treatment of cells with a methylating agent, such as methyl methanesulfonate (MMS) and Nmethyl-N-nitrosourea (MNU), yields various methylated bases in DNA (Riazuddin and Lindahl, 1978). Organisms possess mechanisms to repair these methylated bases, which are potentially harmful to their genetic material.
K, Sakumi, M, Sekiguchi
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The enigmatic thymine DNA glycosylase

DNA Repair, 2007
When it was first isolated from extracts of HeLa cells in Josef Jiricny's laboratory, the thymine DNA glycosylase (TDG) attracted attention because of its ability to remove thymine, i.e. a normal DNA base, from G.T mispairs. This implicated a function of DNA base excision repair in the restoration of G.C base pairs following the deamination of a 5 ...
Cortázar, Daniel, Kunz, Christophe, Saito, Yusuke, Steinacher, Roland, Schär, Primo   +4 more
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