Results 171 to 180 of about 20,880 (290)
Demonstration of pyrimidine dimer-DNA glycosylase activity in vivo: bacteriophage T4-infected Escherichia coli as a model system [PDF]
Eric H. Radany, E C Friedberg
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Impact of Oxidative DNA Damage and the Role of DNA Glycosylases in Neurological Dysfunction. [PDF]
de Sousa MML+6 more
europepmc +1 more source
Uracil-DNA glycosylase of thermophilic Thermothrix thiopara [PDF]
O. K. Kaboev+2 more
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Summary CRISPR‐Cas‐based cytosine base editors (CBEs) are prominent tools that perform site‐specific and precise C‐to‐T conversions catalysed by cytidine deaminases. However, their use is often constrained by stringent editing preferences for genomic contexts, off‐target effects and restricted editing windows.
Danyel Fernandes Contiliani+7 more
wiley +1 more source
Molecular Dynamics Simulations of a Nucleosome and Free DNA [PDF]
Nucleosomes organize the folding of DNA into chromatin and significantly influence transcription, replication, regulation and repair. All atom molecular dynamics simulations of a nucleosome and of its 146 basepairs of DNA free in solution have been conducted.
arxiv
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse+6 more
wiley +1 more source
Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells. [PDF]
K Wiebauer, Josef Jiricny
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ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung+7 more
wiley +1 more source
Repair and DNA Polymerase Bypass of Clickable Pyrimidine Nucleotides
Clickable nucleosides, most often 5-ethynyl-2′-deoxyuridine (EtU), are widely used in studies of DNA replication in living cells and in DNA functionalization for bionanotechology applications.
Anton V. Endutkin+6 more
doaj +1 more source
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina+3 more
wiley +1 more source