Results 171 to 180 of about 20,880 (290)

Impact of Oxidative DNA Damage and the Role of DNA Glycosylases in Neurological Dysfunction. [PDF]

open access: yesInt J Mol Sci, 2021
de Sousa MML   +6 more
europepmc   +1 more source

Uracil-DNA glycosylase of thermophilic Thermothrix thiopara [PDF]

open access: bronze, 1985
O. K. Kaboev   +2 more
openalex   +1 more source

Harnessing novel cytidine deaminases from the animal kingdom for robust multiplexed base editing in rice

open access: yesPlant Biotechnology Journal, Volume 23, Issue 5, Page 1702-1712, May 2025.
Summary CRISPR‐Cas‐based cytosine base editors (CBEs) are prominent tools that perform site‐specific and precise C‐to‐T conversions catalysed by cytidine deaminases. However, their use is often constrained by stringent editing preferences for genomic contexts, off‐target effects and restricted editing windows.
Danyel Fernandes Contiliani   +7 more
wiley   +1 more source

Molecular Dynamics Simulations of a Nucleosome and Free DNA [PDF]

open access: yesarXiv, 2004
Nucleosomes organize the folding of DNA into chromatin and significantly influence transcription, replication, regulation and repair. All atom molecular dynamics simulations of a nucleosome and of its 146 basepairs of DNA free in solution have been conducted.
arxiv  

A stage‐dependent seed defense response to explain efficient seed transmission of Xanthomonas citri pv. fuscans to common bean

open access: yesPlant, Cell &Environment, EarlyView.
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse   +6 more
wiley   +1 more source

DNA Hypomethylation Is One of the Epigenetic Mechanisms Involved in Salt‐Stress Priming in Soybean Seedlings

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung   +7 more
wiley   +1 more source

Repair and DNA Polymerase Bypass of Clickable Pyrimidine Nucleotides

open access: yesBiomolecules
Clickable nucleosides, most often 5-ethynyl-2′-deoxyuridine (EtU), are widely used in studies of DNA replication in living cells and in DNA functionalization for bionanotechology applications.
Anton V. Endutkin   +6 more
doaj   +1 more source

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

open access: yesPhotochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina   +3 more
wiley   +1 more source

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