Results 161 to 170 of about 2,395,071 (348)

Helicases and DNA dependent ATPases of Sulfolobus solfataricus

open access: yes, 2008
Electronic version does not contain associated previously published materialDNA is susceptible to various types of damage as a result of normal cellular metabolism or from environmental sources.
Richards, Jodi D.
core  

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

Structural and mechanistic insights into the herpes simplex virus type 1 helicase-primase primosome

open access: yesCell Discovery
DNA unwinding and primer synthesis are fundamental processes in genome replication. The human herpes simplex virus type 1 (HSV-1) helicase-primase forms a unique heterotrimeric primosome that is essential for viral DNA unwinding and primer synthesis and ...
Yaqi Wu   +5 more
doaj   +1 more source

Multi‐Omics Analysis Reveals Coordinated Adaptations in Genes, Metabolism, and Gut Microbiota Underpinning Herbivory in Lordiphosa Flies

open access: yesIntegrative Zoology, EarlyView.
Multi‐omics analysis reveals that herbivorous adaptation in Lordiphosa flies arises from coordinated interactions across the genome, transcriptome, and gut microbiota: genomic expansions of detoxification (e.g., cytochrome P450s) and carbohydrate metabolism gene families, transcriptomic upregulation of energy pathways like lipid oxidation and ...
Run Guo   +4 more
wiley   +1 more source

Structures of nucleotide-bound Redondovirus Rep protein link conformation and function.

open access: yesPLoS Pathogens
Circular Rep-encoding single-stranded DNA (CRESS-DNA) virus Rep proteins are multidomain enzymes that mediate viral DNA rolling-circle replication.
Saira Montermoso   +5 more
doaj   +1 more source

Suramin action in African trypanosomes involves a RuvB-like DNA helicase. [PDF]

open access: yesInt J Parasitol Drugs Drug Resist, 2023
Albisetti A   +4 more
europepmc   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

open access: yesAllergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter   +19 more
wiley   +1 more source

Functional interactions of Gp22 and Gp23 with Gp21 DNA helicase define the replication module of dairy-relevant Ceduovirus phage 94p4

open access: yesJournal of Dairy Science
: Lactococcus lactis and Lactococcus cremoris strains play a vital role in dairy fermentations, yet their industrial use is threatened by bacteriophage infections that can lead to production failures.
Anna Santo   +3 more
doaj   +1 more source

Helicase-binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis

open access: yes, 2006
The Bacillus subtilis DnaI, DnaB and DnaD proteins load the replicative ring helicase DnaC onto DNA during priming of DNA replication. Here we show that DnaI consists of a C-terminal domain (Cd) with ATPase and DNA-binding activities and an N-terminal ...
Nicholas Dixon (20136564)   +3 more
core  

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