Results 211 to 220 of about 2,395,071 (348)

Disease-causing missense mutations in human DNA helicase disorders.

Mutation research, 2013
A. Suhasini, R. Brosh
semanticscholar   +1 more source

DDX21 Promotes Breast Cancer Growth and Metastasis via Stimulating RNAPII Elongation During Hypoxia

MedComm, Volume 7, Issue 7, July 2026.
DDX21 triggers CDK9 release from the 7SK RNP complex. DDX21‐CDK9 binding to HIFs drives transcriptional reprogramming during hypoxia. DDX21 enhances breast cancer progression and metastasis. Elevated DDX21 expression correlates with poor prognosis in breast cancer patients.
Guangqiang Li, Mingxia Deng, Leqing Zhu, Zhiwei Lei, Rong Guo, Xiong Liu, Renwang Chen, Xichun Xia, Qiong Wen, Yuanyuan Duan, Yan Chen, Zhinan Yin   +11 more
wiley   +1 more source

The DNA helicase HELQ promotes replication fork reversal in coordination with BRCA2- and FANCD2-mediated repair pathways. [PDF]

Nucleic Acids Res
Dunbayev Y, Chen YJ, Sassi L, Lee EA, Ra JS, Choi M, Mukherjee A, Vasquez KM, Costanzo V, Chi P, Takata KI.   +10 more
europepmc   +1 more source

Skin Cancer Predisposition Genes, Full‐Body Skin Examinations, Familial Disclosure, and Genetic Testing Among High‐Risk Individuals

International Journal of Dermatology, Volume 65, Issue 7, Page 1431-1441, July 2026.
ABSTRACT Background There is a lack of knowledge in full‐body skin examinations (FBSEs) in the context of pathogenic or likely pathogenic variants (PV/LPV) in skin cancer predisposition genes (CPGs). This study assessed the association between carrier status of PV/LPV in skin CPGs and FBSEs and described the patterns of family letter receipt, familial ...
Jincong Q. Freeman, Yu Matsui, Fangyuan Zhao, Olufunmilayo I. Olopade, Dezheng Huo   +4 more
wiley   +1 more source

Deficiency of Werner RecQ-type DNA helicase causes premature malnutrition in zebrafish. [PDF]

iScience
Ujibe K, Kashima M, Kataoka M, Shimada R, Okamoto M, Kobayashi I, Wada S, Matsuda H, Sakamoto A, Hirata H.   +9 more
europepmc   +1 more source

An Adenosine Triphosphate- Dependent 5'-3' DNA Helicase From sk1-Like Lactococcus lactis F13 Phage. [PDF]

Front Microbiol, 2022
Chmielewska-Jeznach M, Steczkiewicz K, Kobyłecki K, Bardowski JK, Szczepankowska AK.   +4 more
europepmc   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, Volume 49, Issue 7, Page 4152-4165, July 2026.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

The DNA helicase RTEL1 is involved in the repair of replicative DNA damage independently of the alternative end joining and the DNA-protein cross-link repair pathways in Arabidopsis. [PDF]

Plant J
Goldkuhle L, Lechner L, Capdeville N, Dorn A, Puchta H.   +4 more
europepmc   +1 more source

Tau Pathology Associated With Parkinsonism and Mutation of Mitochondrial DNA Helicase Gene TWNK. [PDF]

Neurol Genet, 2021
Vandenberghe W, Imberechts D, Van Laere K, Jannis L, De Hertogh G, Ronisz A, Thal DR.   +6 more
europepmc   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source