Results 271 to 280 of about 2,395,071 (348)

The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice. [PDF]

PLoS Genet
Horan TS, Ascenção CFR, Mellor C, Wang M, Smolka MB, Cohen PE.   +5 more
europepmc   +1 more source

Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase

Proceedings of the National Academy of Sciences of the United States of America, 2001
H. Cohen, D. Sinclair
semanticscholar   +1 more source

Association mapping for hop cone chemistry and morphology identifies natural beneficial allele stacks

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Efforts are underway to increase the efficiency and precision of selection hop (Humulus lupulus L.) breeding using genomics. Little is known, however, about the genetic control of important traits like α‐and β‐acids contents, oil content, and cone morphological characteristics, all of which play an important role in determining the utility and
Shaun J. Clare, Peter Schmuker, Kayla Altendorf   +2 more
wiley   +1 more source

Chl1p, a DNA Helicase-Like Protein in Budding Yeast, Functions in Sister-Chromatid Cohesion

Genetics, 2004
R. Skibbens
semanticscholar   +1 more source

Genetic identification and characterization of novel loci for flag leaf morphology traits in Chinese endemic wheat

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Flag leaf morphology (FLM) is a critical determinant of wheat (Triticum aestivum L.) photosynthetic efficiency and grain yield. Chinese endemic wheat, a unique genetic reservoir formed by long‐term adaptation to diverse and heterogeneous environments in China, harbors abundant, untapped allelic variation for traits related to environmental ...
Md Nahibuzzaman Lohani, Longxing Su, Lu Lu, Li Yin, Yanlin Liu, Qiang Xu, Yunfeng Jiang, Qiantao Jiang, Guoyue Chen, Yuming Wei, Chunji Liu, Quan Xie, Jian Ma   +12 more
wiley   +1 more source

Loss of SMARCAD1 Mitigates Tauopathy

Aging Cell, Volume 25, Issue 6, June 2026.
Using genetics approaches in a C. elegans transgenic model of tauopathy, we uncover a role for the homolog of human SMARCAD1, a regulator of chromatin dynamics. ABSTRACT Tauopathies are neurodegenerative diseases characterized by the accumulation of misfolded tau protein and include Alzheimer's disease (AD) and related dementia disorders.
Vaishnavi S. Jadhav, Rebecca L. Kow, Asia D. Beale, Misa Baum, Pamela J. McMillan, Caitlin S. Latimer, Nicole F. Liachko, Brian C. Kraemer   +7 more
wiley   +1 more source

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma

British Journal of Pharmacology, Volume 183, Issue 12, Page 3355-3376, June 2026.
Inhibitors of insulin‐degrading enzyme boost PI cytotoxicity through an increased sensitivity of proteasome to PI inhibitors, induction of ISR, DNA damage and Myc down‐regulation. They overcome PI resistance in vitro and induce tumour regression in vivo.
Laetitia Lesire, Rebecca Deprez‐Poulain, Damien Bosc, Florence Leroux, Valerie Landry, Sarah Ourabah, Morgane Tardy, Clara Maillard, Ronan Gealageas, Julie Dumont, Adrien Herledan, Sandrine Warenghem, Manon Cruette, Celine Lenglart, Alexandre Biela, Catherine Piveteau, Eva De Smedt, Catharina Muylaert, Wenguang Liang, Elvira Garcia De Paco, Elina Alaterre, Sara Ovejero, Nicolas Robert, Fabien Delahaye, Wei‐Jen Tang, Peter van Endert, Elke De Bruyne, Jérôme Moreaux, Benoit Deprez   +28 more
wiley   +1 more source

Expanding the Phenotypic Spectrum Associated With Loss‐of‐Function SMARCA4 Variants to Eye Developmental Anomalies

Clinical Genetics, Volume 109, Issue 6, Page 1064-1069, June 2026.
This study expands the clinical spectrum of SMARCA4 by describing a novel phenotype in three unrelated individuals with truncating variants. Distinct from Coffin–Siris syndrome and rhabdoid tumor predisposition, this new association is characterized by ocular malformations, specifically microphthalmia and coloboma.
Bertrand Chesneau, Marjolaine Willems, Abdelhakim Bouazzaoui, Léopoldine Lequeux, Julie Plaisancié, Salima El Chehadeh, Hélène Dollfus, Nicolas Chassaing   +7 more
wiley   +1 more source

Expanding Phenotype of GINS1 Deficiency: A Case Report and Review of the Literature

Clinical Genetics, Volume 109, Issue 6, Page 1076-1080, June 2026.
The authors present a novel case and review of individuals with GINS1 deficiency, causing severe growth restriction and combined immunodeficiency. Only the ninth case of this ultrarare disorder, it highlights the role of these variants in disease, glaucoma as a feature, and the possibility of immunodeficiency without infections in affected individuals.
Michael P. Mackley, Rae Brager, Hannah Geddie, Vicky Breakey, Rebecca Hough, Dimitrios J. Stavropoulos, Vanda McNiven   +6 more
wiley   +1 more source

Plasmodium falciparum DDX31 is DNA helicase localized in nucleolus. [PDF]

Heliyon, 2019
Yasmin R, Chauhan M, Sourabh S, Tuteja R.   +3 more
europepmc   +1 more source