Results 111 to 120 of about 208,982 (285)
Temperature Dependence of the Activity of DNA‐Modifying Enzymes: Endonucleases and DNA Ligase [PDF]
, 1982 Fritz M. Pohl, R. Thomae, Antje KARST
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Advanced Science, EarlyView.In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu +13 more
wiley +1 more source
Mismatch and blunt to protruding-end joining by DNA ligases [PDF]
, 1987 Ryszard Wiaderkiewicz +1 more
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Advanced Science, EarlyView.Norepinephrine/α2B‐adrenoceptor axis promotes the secretion of Notch2 intracellular domain (N2ICD)‐enriched extracellular vesicles (EVs) from macrophages. These EVs deliver N2ICD into fibroblasts, thereby inducing their activation. Deletion of Notch2 or α2B‐AR in macrophages disrupts N2ICD‐enriched EV formation and alleviates kidney fibrosis in mice ...
Huiwen Ren +14 more
wiley +1 more source
Purification of HB8 DNA Ligase by Red Sepharose Chromatography [PDF]
, 1986 Miho Takahashi +2 more
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Advanced Science, EarlyView.Draper is evolutionarily conserved across most insect species. Loss of Draper inhibits autophagy activation, delaying middle silk gland degradation in the silkworm during metamorphosis. Draper interacts with autophagy ‐ related protein 3 (ATG3) to orchestrate autophagosome formation—a process essential for silk gland degradation during the larval‐pupal
Shiyu Zou +9 more
wiley +1 more source
Correlation between anthracycline structure and human DNA ligase inhibition [PDF]
, 1991 Giovanni Ciarrocchi +4 more
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Advanced Science, EarlyView.Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh +11 more
wiley +1 more source
R2D ligase: Unveiling a novel DNA ligase with surprising DNA‐to‐RNA ligation activity
Biotechnology JournalAbstractDNA ligases catalyze bond formation in the backbone of nucleic acids via the formation of a phosphodiester bond between adjacent 5′ phosphates and 3′ hydroxyl groups on one strand of the duplex. While DNA ligases preferentially ligate single breaks in double‐stranded DNA (dsDNA), they are capable of ligating a multitude of other nucleic acid ...
Sigurd Eidem Gundesø +10 more
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