Results 201 to 210 of about 208,982 (285)

Altered DNA ligase activity in human disease. [PDF]

open access: yesMutagenesis, 2020
Tomkinson AE   +2 more
europepmc   +1 more source

An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. [PDF]

open access: yesNucleic Acids Res, 2021
Hammel M   +9 more
europepmc   +1 more source

UHRF1 Controls the Timing of RAD51 Removal During DNA Damage Repair Through Suppressing RFWD3

open access: yesAdvanced Science, EarlyView.
We demonstrate here that the recombinase RAD51 is protected by UHRF1 through ubiquitinating RFWD3, an E3 for RAD51, and this very process is inhibited by RAD51, leading to a triple negative feedback circuit that ensures appropriate levels of RFWD3 and RAD51 for DNA damage response. Abstract The RAD51 recombinase is evolutionarily conserved critical for
Guangxue Liu   +4 more
wiley   +1 more source

The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer. [PDF]

open access: yesIn Vivo
Deng Y   +12 more
europepmc   +1 more source

NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV. [PDF]

open access: yesNucleic Acids Res, 2020
Zhao B   +3 more
europepmc   +1 more source

RING‐Between‐RING‐Type E3 Ligase Ariadne‐Like Protein 8 Negatively Regulates Plant Virus Infection by Targeting a Viral Movement Protein

open access: yesAdvanced Science, EarlyView.
The plant RING‐between‐RING (RBR)‐type E3 ligase, Ariadne‐like protein 8 (ARI8), ubiquitinates and degrades a viral movement protein, restricting virus spread. ARI8 also inhibits other triple gene block 1 (TGB1)‐containing viruses, revealing a broad‐spectrum antiviral role.
Wenli Li   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy