Results 211 to 220 of about 2,416,649 (374)
Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. [PDF]
Sverzhinsky A, Tomkinson AE, Pascal JM.
europepmc +1 more source
DNA Ligase I and Proliferating Cell Nuclear Antigen Form a Functional Complex
Samson Tom +3 more
openalex +1 more source
Functional Dissection of the DNA Interface of the Nucleotidyltransferase Domain of Chlorella Virus DNA Ligase [PDF]
Poulami Samai, Stewart Shuman
openalex +1 more source
Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo +11 more
wiley +1 more source
Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect Cells. [PDF]
Rashid I +9 more
europepmc +1 more source
SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV.
G. E. Greco +5 more
semanticscholar +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source

