Results 111 to 120 of about 81,238 (327)
Mismatch discrimination and sequence bias during end-joining by DNA ligases. [PDF]
Nucleic Acids Res, 2022 Bilotti K +5 more
europepmc +1 more source
The novel E3 ligase of PPAR?? TRIM25 regulates adipocyte differentiation [PDF]
, 2018 Department of Biological SciencesPeroxisome proliferator-activated receptor ?? (PPAR??) is a ligand-dependent transcription factor which regulates glucose homeostasis and adipocyte differentiation.
Lee, Jae Min
core
Advanced Science, EarlyView.CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian +12 more
wiley +1 more source
How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair Pathway
Frontiers in Genetics, 2016 Fanconi Anemia (FA) is a rare human genetic disorder characterized by developmental defects, bone marrow failure and cancer predisposition, primarily due to a deficiency in the repair of DNA interstrand crosslinks (ICLs).
Kate eColeman, Tony T Huang
doaj +1 more source
Human DNA ligases I and III have stand-alone end-joining capability, but differ in ligation efficiency and specificity. [PDF]
Nucleic Acids Res, 2023 McNally JR +3 more
europepmc +1 more source
Expression of a DNA‐ligase‐stimulatory factor in Bloom's syndrome cell line GM1492 [PDF]
, 1988 Kerstin Kenne, Siv Ljungquist
openalex +1 more source
Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
Advanced Science, EarlyView.NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source
Smurfs in Protein Homeostasis, Signaling, and Cancer
Frontiers in Oncology, 2018 Protein ubiquitination is an evolutionary conserved highly-orchestrated enzymatic cascade essential for normal cellular functions and homeostasis maintenance.
Praveen Koganti +2 more
doaj +1 more source
Advanced Science, EarlyView.This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source