Results 261 to 270 of about 81,238 (327)

Human DNA ligase i (ligi) gene and risk of cervical cancer in North Indian women.

, 2013
K. Paul Satinder
openalex   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Decoding neddylation in malignancies: molecular mechanisms, biological functions, therapeutic resistance, and clinical potential. [PDF]

Cell Death Dis
Deng N, Sun Q, Yu X, Li T, Sun J, Jia S, Ma S, Liu W, Zhou H.   +8 more
europepmc   +1 more source

DNA Ligase I Deficiency [PDF]

, 2020
openaire   +1 more source

Deletion of <i>CnLIG4</i> DNA ligase gene in the fungal pathogen <i>Cryptococcus neoformans</i> elevates homologous recombination efficiency

, 2010
Kiminori Shimizu, Hao-Man Li, Eric V. Virtudazo, Akira Watanabe, Katsuhiko Kamei, Masashi Yamaguchi, Susumu Kawamoto   +6 more
openalex   +2 more sources

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

The role of neddylation in colorectal cancer and its therapeutic potential. [PDF]

Discov Oncol
Mi C, Cui F, Wang S, Du Y, Li Y, Yang H.
europepmc   +1 more source

V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder.

, 1993
Ching‐Lin Hsieh, C.F. Arlett, Michael R. Lieber   +2 more
openalex   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

Small-molecule degron mimetics for targeted protein degradation. [PDF]

Essays Biochem
Liu X.
europepmc   +1 more source