Results 291 to 300 of about 79,069 (319)

Pathological roles of ubiquitination and deubiquitination systems in sepsis-induced myocardial dysfunction. [PDF]

Biomol Biomed
Wang Z, Sun S, Huang L, Chen X, Xu H, Ma H, Xiao M, Wang L.   +7 more
europepmc   +1 more source

A new era in cancer therapy: targeting the Proteasome-Bcl-2 axis. [PDF]

J Exp Clin Cancer Res
Soni S, Anang V, Zhao Y, Horowitz JC, Nho RS, Mebratu YA.   +5 more
europepmc   +1 more source

Chemical and genetic molecular glues to degrade CoREST corepressors. [PDF]

Acta Pharm Sin B
Song YQ, Li Q, Sheng C.
europepmc   +1 more source

Deubiquitinase-Targeting Chimeras Mediated Stabilization of Tumor Suppressive E3 Ligase Proteins as a Strategy for Cancer Therapy. [PDF]

J Am Chem Soc
Chen L, Deng Z, Xiong Y, Liu J, Huang D, Wang J, Chen Y, Inuzuka H, Xie L, Chen X, Jin J, Wei W.   +11 more
europepmc   +1 more source

TRIM52 maintains cellular fitness and is under tight proteolytic control by multiple giant E3 ligases. [PDF]

Nat Commun
Shulkina A, Hacker K, Ehrmann JF, Budroni V, Mandlbauer A, Bock J, Grabarczyk DB, Edobor G, Cochella L, Clausen T, Versteeg GA.   +10 more
europepmc   +1 more source

Proteome-wide microarray-based screening of PAR-binding proteins. [PDF]

Nucleic Acids Res
Gu Kang B, Kang SU, Jin Kim J, Kwon JS, Gagné JP, Yun Lee S, Kim S, Lee KS, Ha S, Seop Jeong J, Lee YI, Zhu H, Kim D, Poirier GG, Chul Kang H, Dawson VL, Dawson TM.   +16 more
europepmc   +1 more source

Ubiquitination in macrophage plasticity: from inflammatory to immunometabolic pathways. [PDF]

Front Immunol
Liu J, Paolino M.
europepmc   +1 more source

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Eukaryotic DNA ligases

Mutation Research/DNA Repair, 1990
Recent studies on eukaryotic DNA ligases are briefly reviewed. The two distinguishable enzymes from mammalian cells, DNA ligase I and DNA ligase II, have been purified to homogeneity and characterized biochemically. Two distinct DNA ligases have also been identified in Drosophila melanogaster embryos.
Alan E. Tomkinson, Tomas Lindahl, Dana D. Lasko   +2 more
openaire   +3 more sources

Mammalian DNA ligases

BioEssays, 1997
AbstractDNA joining enzymes play an essential role in the maintenance of genomic integrity and stability. Three mammalian genes encoding DNA ligases, LIG1, LIG3 and LIG4, have been identified. Since DNA ligase II appears to be derived from DNA ligase III by a proteolytic mechanism, the three LIG genes can account for the four biochemically distinct DNA
David S. Levin, Alan E. Tomkinson
openaire   +3 more sources