Results 11 to 20 of about 2,394,908 (263)
Excitonic AND Logic Gates on DNA Brick Nanobreadboards [PDF]
ACS Photonics, 2015 Abstract A promising application of DNA self-assembly is the fabrication of chromophore-based excitonic devices. DNA brick assembly is a compelling method for creating programmable nanobreadboards on which chromophores may be rapidly and easily repositioned to prototype new excitonic devices, optimize device operation, and induce ...
Cannon, Brittany L. +8 more
openaire +4 more sources
Supplementary. Logic gates based on DNA aptamers
, 2020 Supplementary.
Andrianova Mariia, Kuznetsov Alexander
openaire +3 more sources
Nuclease-containing media for resettable operation of DNA logic gates
Chemical Communications, 2015 A system which enables DNA logic gates to respond multiple times to the addition of oligonucleotide inputs was developed. This system does not require any operator action to achieve reset.
O'Steen, Martin R. +2 more
core +5 more sources
DNA Logic Circuits Based on Accurate Step Function Gate [PDF]
IEEE Access, 2020 DNA molecular as the material for logical computing and information storage has been widely applied. An important mechanism for DNA logical computing is the toehold-mediated DNA Strand Displacement (DSD).
Congzhou Chen +4 more
doaj +3 more sources
Divide and control: split design of multi-input DNA logic gates. [PDF]
Chem Commun (Camb), 2015 Logic gates made of DNA have received significant attention as biocompatible building blocks for molecular circuits. The majority of DNA logic gates, however, are controlled by the minimum number of inputs: one, two or three. Here we report a strategy to
Gerasimova YV, Kolpashchikov DM.
europepmc +3 more sources
Frontiers in Synthetic BiologyOrthogonal repressor-based logic gates have enabled the predictive design of genetic circuits using automated design algorithms. However, engineering complex genetic circuits has been limited by the availability of transcriptional logic gates that are ...
Nathaniel Howitz +4 more
doaj +2 more sources
Antibody Activation using DNA‐Based Logic Gates
Angewandte Chemie International Edition, 2015 AbstractOligonucleotide‐based molecular circuits offer the exciting possibility to introduce autonomous signal processing in biomedicine, synthetic biology, and molecular diagnostics. Here we introduce bivalent peptide–DNA conjugates as generic, noncovalent, and easily applicable molecular locks that allow the control of antibody activity using toehold‐
Brian M. G. Janssen +3 more
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Aptamer-Binding Directed DNA Origami Pattern for Logic Gates
ACS Applied Materials & Interfaces, 2016 In this study, an aptamer-substrate strategy is introduced to control programmable DNA origami pattern. Combined with DNA aptamer-substrate binding and DNAzyme-cutting, small DNA tiles were specifically controlled to fill into the predesigned DNA origami frame.
Jing, Yang +4 more
openaire +3 more sources
A Cascaded DNA Nanocircuit for Multi-Signal-Responsive Precision siRNA Delivery in Cancer Therapy. [PDF]
Adv Sci (Weinh)A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Zhao Y +14 more
europepmc +2 more sources
Antigen-Triggered Logic-Gating of DNA Nanodevices [PDF]
Journal of the American Chemical Society, 2021 Synthetic nanoscale devices that reconfigure dynamically in response to physiological stimuli could offer new avenues for diagnostics and therapy. Here, we report a strategy for controlling the state of DNA nanodevices based on sensing antigens with IgG antibodies.
Engelen, Wouter +4 more
openaire +2 more sources