Results 171 to 180 of about 2,686,549 (398)

DNA‐Cytosine methylation in E. coli MRE 600 cells [PDF]

, 1976
Irina Bogdarina, L. M. Vagabova, Yа. I. Buryanov   +2 more
openalex   +1 more source

DNA methylation age of blood predicts all-cause mortality in later life

Genome Biology, 2015
DNA methylation levels change with age. Recent studies have identified biomarkers of chronological age based on DNA methylation levels. It is not yet known whether DNA methylation age captures aspects of biological age.
R. Marioni, Sonia H. Shah, A. McRae, Brian H. Chen, E. Colicino, S. Harris, J. Gibson, A. Henders, P. Redmond, S. Cox, A. Pattie, J. Corley, L. Murphy, N. Martin, G. Montgomery, A. Feinberg, M. D. Fallin, Michael L. Multhaup, A. Jaffe, R. Joehanes, J. Schwartz, A. Just, K. Lunetta, J. Murabito, J. Starr, S. Horvath, A. Baccarelli, D. Levy, P. Visscher, N. Wray, I. Deary   +30 more
semanticscholar   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Methylation of DNA in early development: 5-methyl cytosine content of DNA in sea urchin sperm and embryos [PDF]

, 1978
James M. Pollock, Marcia Swihart, Taylor J.Herbert   +2 more
openalex   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source

Clonal inheritance of the pattern of DNA methylation in mouse cells. [PDF]

, 1982
Reuven Stein, Yosef Gruenbaum, Yaakov Pollack, Aharon Razin, Howard Cedar   +4 more
openalex   +1 more source

Digital Bioassays on the Slipchip Microfluidic Devices

Advanced Sensor Research, EarlyView.
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo, Ziqing Yu, Weiyuan Lyu, Yang Luo, Lei Xu, Feng Shen   +5 more
wiley   +1 more source

Restriction and modification in Bacillus subtilis: DNA methylation potential of the related bacteriophages Z, SPR, SP beta, phi 3T, and rho 11 [PDF]

, 1983
Mario Noyer-Weidner, Stefan Jentsch, B. Pawlek, Ursula Günthert, Thomas A. Trautner   +4 more
openalex   +1 more source

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source