Results 281 to 290 of about 2,686,549 (398)

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

The advances of DNA methylation in the liquid biopsy for the detection of lung cancer. [PDF]

Front Oncol
Chen Y, Peng S, Wang C.
europepmc   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Epigenetic Therapies in Melanoma-Targeting DNA Methylation and Histone Modification. [PDF]

Biomedicines
Tigu AB, Ivancuta A, Uhl A, Sabo AC, Nistor M, Mureșan XM, Cenariu D, Timis T, Diculescu D, Gulei D.   +9 more
europepmc   +1 more source

The combination of DNA methylation and H1 histone binding inhibits the action of a restriction nuclease on plasmid DNA

, 1991
Makoto Higurashi, R. David Cole
openalex   +1 more source

X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse [PDF]

, 1996
Laura Carrel, Christine Clemson, John M. Dunn, Andrew P. Miller, Patricia A. Hunt, Jeanne B. Lawrence, Huntington F. Willard   +6 more
openalex   +1 more source

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

Advanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu, Jie Zhang, Hengxing Chen, Haobin Hou, Huanjie Chen, Rongman Xie, Yanlei Chen, Jian Zhang, Dehua Liu, Leping Yan, Rui L. Reis, Joaquim M. Oliveira, Yulong He, Li Zhong, Qinbo Cai, Dongjie Yang   +15 more
wiley   +1 more source

Transcription Dynamics and DNA Methylation Responses to Growth Modification. [PDF]

Mar Biotechnol (NY)
Christensen KA, Collette É, Perley D, Sakhrani D, Muttray AF, Leggatt RA, Biagi CA, Koop BF, Devlin RH.   +8 more
europepmc   +1 more source

The Relationship Between DNA Methylation and Chromosome Imprinting in the Coccid Planococcus citri [PDF]

, 1999
Silvia Bongiorni, Orietta Cintio, Giorgio Prantera   +2 more
openalex   +1 more source

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Advanced Science, EarlyView.
Plasmonic molecular entrapment (PME) is label‐free detection and quantification method for DNA methylation. This technique provides direct hotspot site generation around target analytes, overcoming mismatch geometrical properties. The PME demonstrates superior SERS performance and quantification capability, offering promising potential for epigenetic ...
Muhammad Shalahuddin Al Ja'farawy, Vo Thi Nhat Linh, Chaewon Mun, Jun‐Yeong Yang, Jun Young Kim, Rowoon Park, Sung‐Gyu Park, Dong‐Ho Kim, Min‐Young Lee, Ho Sang Jung   +9 more
wiley   +1 more source