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Developmental Genetics, 1989
Article de synthese sur le role dans l'expression genique differentielle de la methylation des bases de l'ADN pendant le developpement des ...
J M, Magill, C W, Magill
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Article de synthese sur le role dans l'expression genique differentielle de la methylation des bases de l'ADN pendant le developpement des ...
J M, Magill, C W, Magill
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Molecular Immunology, 2006
DNA methylation is an epigenetic phenomenon known to play an increasingly important role in the etiology of cancer. Changes in DNA methylation patterns particularly in the promoter region of genes either in the form of hypomethylation or hypermethylation can have profound effects on gene expression.
Gopal, Gopisetty +2 more
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DNA methylation is an epigenetic phenomenon known to play an increasingly important role in the etiology of cancer. Changes in DNA methylation patterns particularly in the promoter region of genes either in the form of hypomethylation or hypermethylation can have profound effects on gene expression.
Gopal, Gopisetty +2 more
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1984
The interrelationship between sister chromatid exchange (SCE) formation and DNA methylation was studied in Chinese hamster V79 and Indian muntjac cells. A DNA methylation inhibitor, 5-azacytidine (5AzaC), induced SCEs only when it had been present in cells for at least 2 rounds of DNA replication.
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The interrelationship between sister chromatid exchange (SCE) formation and DNA methylation was studied in Chinese hamster V79 and Indian muntjac cells. A DNA methylation inhibitor, 5-azacytidine (5AzaC), induced SCEs only when it had been present in cells for at least 2 rounds of DNA replication.
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2010
DNA methylation is one of the most intensely studied epigenetic modifications in mammals. In normal cells, it assures the proper regulation of gene expression and stable gene silencing. DNA methylation is associated with histone modifications and the interplay of these epigenetic modifications is crucial to regulate the functioning of the genome by ...
Marta, Kulis, Manel, Esteller
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DNA methylation is one of the most intensely studied epigenetic modifications in mammals. In normal cells, it assures the proper regulation of gene expression and stable gene silencing. DNA methylation is associated with histone modifications and the interplay of these epigenetic modifications is crucial to regulate the functioning of the genome by ...
Marta, Kulis, Manel, Esteller
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2006
DNA in plants is highly methylated, containing 5-methylcytosine (m5C) and N6-methyladenine (m6A); m5C is located mainly in symmetrical CG and CNG sequences but it may occur also in other non-symmetrical contexts. m6A but not m5C was found in plant mitochondrial DNA. DNA methylation in plants is species-, tissue-, organelle- and age-specific.
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DNA in plants is highly methylated, containing 5-methylcytosine (m5C) and N6-methyladenine (m6A); m5C is located mainly in symmetrical CG and CNG sequences but it may occur also in other non-symmetrical contexts. m6A but not m5C was found in plant mitochondrial DNA. DNA methylation in plants is species-, tissue-, organelle- and age-specific.
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2009
In order to maintain normal function and homeostasis, appropriate gene expression is critical in individual cells. Aberrant gene expression can induce disordered conditions. Regulation of gene expression is not fully known yet but current evidence indicates that epigenetics, a phenomenon that affects gene expression without changes in DNA base pairs (1)
Choi Sang Woon +2 more
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In order to maintain normal function and homeostasis, appropriate gene expression is critical in individual cells. Aberrant gene expression can induce disordered conditions. Regulation of gene expression is not fully known yet but current evidence indicates that epigenetics, a phenomenon that affects gene expression without changes in DNA base pairs (1)
Choi Sang Woon +2 more
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2018
DNA methylation is a process by which methyl groups are added to cytosine or adenine. DNA methylation can change the activity of the DNA molecule without changing the sequence. Methylation of 5-methylcytosine (5mC) is widespread in both eukaryotes and prokaryotes, and it is a very important epigenetic modification event, which can regulate gene ...
Lingfang, Feng, Jianlin, Lou
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DNA methylation is a process by which methyl groups are added to cytosine or adenine. DNA methylation can change the activity of the DNA molecule without changing the sequence. Methylation of 5-methylcytosine (5mC) is widespread in both eukaryotes and prokaryotes, and it is a very important epigenetic modification event, which can regulate gene ...
Lingfang, Feng, Jianlin, Lou
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DNA Methylation in Schizophrenia
2017Schizophrenia is a highly heritable psychiatric condition that displays a complex phenotype. A multitude of genetic susceptibility loci have now been identified, but these fail to explain the high heritability estimates of schizophrenia. In addition, epidemiologically relevant environmental risk factors for schizophrenia may lead to permanent changes ...
Pries, Lotta-katrin +2 more
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Immunoprecipitation of Methylated DNA
2009DNA methylation contributes to the regulation of long-term gene repression by enabling the recruitment of transcriptional repressor complexes to methylated cytosines. Several methods for detecting DNA methylation at the gene-specific and genome-wide levels have been developed.
Anita L, Sørensen, Philippe, Collas
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