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2018
DNA methylation is a process by which methyl groups are added to cytosine or adenine. DNA methylation can change the activity of the DNA molecule without changing the sequence. Methylation of 5-methylcytosine (5mC) is widespread in both eukaryotes and prokaryotes, and it is a very important epigenetic modification event, which can regulate gene ...
Lingfang, Feng, Jianlin, Lou
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DNA methylation is a process by which methyl groups are added to cytosine or adenine. DNA methylation can change the activity of the DNA molecule without changing the sequence. Methylation of 5-methylcytosine (5mC) is widespread in both eukaryotes and prokaryotes, and it is a very important epigenetic modification event, which can regulate gene ...
Lingfang, Feng, Jianlin, Lou
openaire +2 more sources
DNA Methylation in Schizophrenia
2017Schizophrenia is a highly heritable psychiatric condition that displays a complex phenotype. A multitude of genetic susceptibility loci have now been identified, but these fail to explain the high heritability estimates of schizophrenia. In addition, epidemiologically relevant environmental risk factors for schizophrenia may lead to permanent changes ...
Pries, Lotta-katrin +2 more
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2009
In order to maintain normal function and homeostasis, appropriate gene expression is critical in individual cells. Aberrant gene expression can induce disordered conditions. Regulation of gene expression is not fully known yet but current evidence indicates that epigenetics, a phenomenon that affects gene expression without changes in DNA base pairs (1)
Choi Sang Woon +2 more
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In order to maintain normal function and homeostasis, appropriate gene expression is critical in individual cells. Aberrant gene expression can induce disordered conditions. Regulation of gene expression is not fully known yet but current evidence indicates that epigenetics, a phenomenon that affects gene expression without changes in DNA base pairs (1)
Choi Sang Woon +2 more
openaire +2 more sources
2006
DNA in plants is highly methylated, containing 5-methylcytosine (m5C) and N6-methyladenine (m6A); m5C is located mainly in symmetrical CG and CNG sequences but it may occur also in other non-symmetrical contexts. m6A but not m5C was found in plant mitochondrial DNA. DNA methylation in plants is species-, tissue-, organelle- and age-specific.
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DNA in plants is highly methylated, containing 5-methylcytosine (m5C) and N6-methyladenine (m6A); m5C is located mainly in symmetrical CG and CNG sequences but it may occur also in other non-symmetrical contexts. m6A but not m5C was found in plant mitochondrial DNA. DNA methylation in plants is species-, tissue-, organelle- and age-specific.
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Am-bivalency towards DNA methylation
Nature Reviews Molecular Cell Biology, 2020Zlotorynski Eytan, Eytan Zlotorynski
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Dynamics and function of DNA methylation in plants
Nature Reviews Molecular Cell Biology, 2018Jian-Kang Zhu +2 more
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The diverse roles of DNA methylation in mammalian development and disease
Nature Reviews Molecular Cell Biology, 2019Deborah Bourc'His +2 more
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DNA methylation pathways and their crosstalk with histone methylation
Nature Reviews Molecular Cell Biology, 2015Steven Jacobsen +2 more
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The roles of DNA, RNA and histone methylation in ageing and cancer
Nature Reviews Molecular Cell Biology, 2019Mark A Dawson +2 more
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