Results 241 to 250 of about 1,977,316 (301)

A Collaborative Framework for Coordinated Analysis Developed by the Genetics of DNA Methylation Consortium

Min J, Ruiz-Arenas C, Awoniran OM, Castellini-Pérez O, Jonkman TH, Llonga N, Ting Q, Raitoharju E, Rajić S, Rodríguez-Romero MD, Artigas MS, Tang H, Dongen Jv, Wang S, Yang J, Zhang X, Bell JT, Gaunt TR, Heijmans B, Hemani G, Mill J, Relton C, Hannon E.   +22 more
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Long-Term Impact of Cumulative Hyperglycaemia on DNA Methylation and its Role in Diabetic Kidney Disease

Luo X, Syreeni A, Hill C, Smyth LJ, Dahlström EH, Mutter S, Chen Z, Natarajan R, Pan S, Parton A, Jackson H, McKay G, Susztak K, Hirschhorn JN, Florez JC, Maxwell AP, Groop P, McKnight AJ, Sandholm N.   +18 more
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DNA Methylation Analysis

2023
DNA methylation of promoter CpG islands silences their downstream genes, and enhancer methylation can be associated with decreased or increased gene expression. DNA methylation alterations in normal and diseased cells provide rich information, such as tissue origin, disease risk, patient response, and prognosis.
Naoko, Hattori, Yu-Yu, Liu, Toshikazu, Ushijima   +2 more
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Favoritism in DNA Methylation

Cancer Prevention Research, 2009
Abstract This perspective on Candiloro and Dobrovic (beginning on p. 862 in this issue of the journal) highlights the interplay between epigenetic aberrations and underlying DNA sequence changes and illustrates how these alterations may predispose individuals to cancer.
Hitchins, Megan P., Ward, Robyn L.
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DNA Methylation and Carcinogenesis

Biochemistry (Moscow), 2001
In the world of easy things truth is opposed to lie; in the world of complicated things one profound truth is opposed to another not less profound than the first. Neils Bohr The hypothesis of the exclusively genetic origin of cancer ("cancer is a disease of genes, a tumor without any damage to the genome does not exist") dominated in the oncology until
A V, Lichtenstein, N P, Kisseljova
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Dna Methylation in Eukaryote

Critical Reviews in Biochemistry, 1982
The DNA of higher eukaryotes contains one minor base, namely 5-methylcytosine. The distribution of this minor base between different species and different DNA fractions will be considered together with the actual sequences methylated. The properties of the enzyme responsible for DNA modification will be reviewed, particular note being paid to the ...
R. L. P. Adams, R. H. Burdon, J. Herbert Taylor   +2 more
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DNA Methylation and DNA Structure

1984
Novel DNA substrates, such as hemimethylated DNA, supercoiled, partially or fully relaxed DNA, either intact or UV-irradiated, have been used to study either some aspects of the mechanism of DNA methylation or some aspects of the effect of pathological and physiological DNA methylation on DNA conformation.
S, Spadari, G, Pedrali-Noy, M, Ciomei, A, Rebuzzini, U, Hübscher, G, Ciarrocchi   +5 more
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Methylation of DNA in Prokaryotes

1993
A much wider variety of biological functions of postreplicative DNA methylation is observed in prokaryotes than in eukaryotes. In eukaryotes DNA methylation is primarily a means of the control of gene expression. Many chapters of this book are devoted to various aspects of this function. In prokaryotes, DNA methylation affects such diverse phenomena as
M, Noyer-Weidner, T A, Trautner
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DNA methylation and cancer

Journal of Cellular Physiology, 2000
The methylation of DNA is an epigenetic modification that can play an important role in the control of gene expression in mammalian cells. The enzyme involved in this process is DNA methyltransferase, which catalyzes the transfer of a methyl group from S-adenosyl-methionine to cytosine residues to form 5-methylcytosine, a modified base that is found ...
R L, Momparler, V, Bovenzi
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