Results 251 to 260 of about 1,977,316 (301)
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Annual Review of Plant Physiology and Plant Molecular Biology, 1998
▪ Abstract Methylation of cytosine residues in DNA provides a mechanism of gene control. There are two classes of methyltransferase in Arabidopsis; one has a carboxy-terminal methyltransferase domain fused to an amino-terminal regulatory domain and is similar to mammalian methyltransferases.
E. J., Finnegan +3 more
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▪ Abstract Methylation of cytosine residues in DNA provides a mechanism of gene control. There are two classes of methyltransferase in Arabidopsis; one has a carboxy-terminal methyltransferase domain fused to an amino-terminal regulatory domain and is similar to mammalian methyltransferases.
E. J., Finnegan +3 more
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DNA methylation and embryogenesis
1993A large number of studies have documented the methylation patterns of individual genes and repeated sequences in different tissues of various mammalian species. This has revealed a consistent picture of DNA modification where each cell type has its characteristic pattern.
A, Razin, H, Cedar
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Trends in Genetics, 1999
The methylation of CpG islands is often equated with transcriptional inactivity and there is overwhelming evidence that this is the case for islands located in gene promoters. Such methylation is probably part of a mechanism to permanently silence the activities of genes, including those on the inactive X chromosome. Not all CpG islands and methylation
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The methylation of CpG islands is often equated with transcriptional inactivity and there is overwhelming evidence that this is the case for islands located in gene promoters. Such methylation is probably part of a mechanism to permanently silence the activities of genes, including those on the inactive X chromosome. Not all CpG islands and methylation
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2010
Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation. Global changes in the epigenetic landscape are a hallmark of cancer.
Yoshihisa, Watanabe, Masato, Maekawa
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Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation. Global changes in the epigenetic landscape are a hallmark of cancer.
Yoshihisa, Watanabe, Masato, Maekawa
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Current Opinion in Genetics & Development, 1995
Recent advances have expanded our understanding of the processes underlying the establishment, maintenance, and elaboration of DNA methylation patterns in eukaryotes. The functional significance of DNA methylation is sought in a comparison of results on a variety of epigenetic phenomena in different eukaryotes. The recent development of DNA methylation
R A, Martienssen, E J, Richards
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Recent advances have expanded our understanding of the processes underlying the establishment, maintenance, and elaboration of DNA methylation patterns in eukaryotes. The functional significance of DNA methylation is sought in a comparison of results on a variety of epigenetic phenomena in different eukaryotes. The recent development of DNA methylation
R A, Martienssen, E J, Richards
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Biochemical and Biophysical Research Communications, 1983
The lower amount of 5 methylcytosine in DNA from bull sperm relative to DNA of other bovine tissues is a result of the absence of this minor base from several of the satellite DNAs in sperm. This applies particularly to the 1.715, 1.711b and 1.709 satellites and less so to the 1.706 and 1.711a satellites.
R L, Adams, R H, Burdon, J, Fulton
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The lower amount of 5 methylcytosine in DNA from bull sperm relative to DNA of other bovine tissues is a result of the absence of this minor base from several of the satellite DNAs in sperm. This applies particularly to the 1.715, 1.711b and 1.709 satellites and less so to the 1.706 and 1.711a satellites.
R L, Adams, R H, Burdon, J, Fulton
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Gene, 1988
Both replicative and postreplicative nuclear DNA (nDNA) methylation, with the formation of 5-methylcytosine (mC) residues, occurs in plants. These two types of enzymatic DNA modification are different in amount and nucleotide sequence of methylatable sites, as well as in sensitivity to phytohormones, temperature and various inhibitors of DNA ...
B F, Vanyushin, M D, Kirnos
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Both replicative and postreplicative nuclear DNA (nDNA) methylation, with the formation of 5-methylcytosine (mC) residues, occurs in plants. These two types of enzymatic DNA modification are different in amount and nucleotide sequence of methylatable sites, as well as in sensitivity to phytohormones, temperature and various inhibitors of DNA ...
B F, Vanyushin, M D, Kirnos
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Gene, 2006
Very recent investigations have provided evidence for a higher DNA methylation level in polar and sub-antarctic fishes compared to temperate/tropical fishes, the latter being in turn higher than the DNA methylation level of warm-blooded vertebrates. These results confirm and extend the finding [Jabbari, K., Cacciò, S., Pais de Barros, J.P., Desgres, J.,
Annalisa, Varriale, Giorgio, Bernardi
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Very recent investigations have provided evidence for a higher DNA methylation level in polar and sub-antarctic fishes compared to temperate/tropical fishes, the latter being in turn higher than the DNA methylation level of warm-blooded vertebrates. These results confirm and extend the finding [Jabbari, K., Cacciò, S., Pais de Barros, J.P., Desgres, J.,
Annalisa, Varriale, Giorgio, Bernardi
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Annals of the New York Academy of Sciences, 2004
Abstract: Early detection of cancer would facilitate better management of patients, because survival is greatly affected by stage of presentation. Circulating nucleic acids represent a biomarker that might be used in the early detection of cancer. In addition, such biomarkers could potentially be used to follow the progression of patients with cancer.
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Abstract: Early detection of cancer would facilitate better management of patients, because survival is greatly affected by stage of presentation. Circulating nucleic acids represent a biomarker that might be used in the early detection of cancer. In addition, such biomarkers could potentially be used to follow the progression of patients with cancer.
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Methyl DNA Immunoprecipitation
2009Epigenetics is the study of heritable changes in gene expression. Chromatin immunoprecipitation (ChIP) and methylation status analysis of genes have been applied to the study of epigenetic modifications, often perturbed in human cancer. ChIP is a technique allowing the analysis of the protein association with specific genomic regions in the context of ...
Juana, Magdalena, Jean-Jacques, Goval
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